SCHEMBL18174697

SCHEMBL18174697

Cc1ccc(-c2ccc(-c3c4ccccc4c(-c4ccc(-c5ncccc5C)cc4)c4ccccc34)cc2)cn1

nearest known ligand 0.47

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
CYP2A6 P11509 1/20 0.47
CNR2 P34972 1/20 0.44
TRPV1 Q8NER1 8/20 0.39
METAP2 P50579 1/20 0.38
DHODH Q02127 1/20 0.37
HPGDS O60760 1/20 0.36
ABL1 P00519 1/20 0.36
PDK1 Q15118 2/20 0.35
NPC1 O15118 1/20 0.35
PKM P14618 1/20 0.35
RAB9A P51151 1/20 0.35
GBA1 P04062 1/20 0.35
HSD17B10 Q99714 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15161070 0.91 CYP2A6 (0.46) CYP2A6CNR2TRPV1METAP2DHODH
SCHEMBL18174567 0.89 CYP2A6 (0.53) CYP2A6CNR2TRPV1METAP2DHODH
SCHEMBL17532877 0.86 NPC1 (0.44) CYP2A6HPGDSABL1NPC1PKM
SCHEMBL18174654 0.83 DYRK1A (0.44) CYP2A6CNR2TRPV1PDK1
SCHEMBL16114340 0.82 CYP2A6 (0.67) CYP2A6CNR2TRPV1METAP2HPGDS
SCHEMBL18174710 0.81 IMPDH2 (0.45) HPGDSNPC1PKMRAB9AHSD17B10
SCHEMBL15977631 0.81 CYP2A6 (0.46) CYP2A6CNR2TRPV1DHODHPDK1
SCHEMBL15160986 0.81 CYP2A6 (0.46) CYP2A6CNR2TRPV1DHODHPDK1
SCHEMBL18174675 0.81 CYP2A6 (0.50) CYP2A6CNR2TRPV1METAP2DHODH
SCHEMBL18174690 0.81 CYP2A6 (0.44) CYP2A6CNR2DHODHHPGDSNPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9478750-B2 Anthracene derivative and organic electroluminescent element using the same JNC CORPORATION (JP) 2016-10-25 US disclosed
US-9478750-B2 Anthracene derivative and organic electroluminescent element using the same JNC CORPORATION (JP) 2016-10-25 US disclosed