SCHEMBL18174584

SCHEMBL18174584

Cc1c(-c2cccnc2)cccc1-c1c2ccccc2c(-c2cccc(-c3cccnc3)c2C)c2cc(-c3ccccc3)ccc12

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP11B1 P15538 3/20 0.44
DHODH Q02127 1/20 0.43
KDM4E B2RXH2 1/20 0.43
LMNA P02545 1/20 0.43
HTT P42858 1/20 0.43
CHEK1 O14757 1/20 0.42
AURKA O14965 1/20 0.42
DAPK3 O43293 1/20 0.42
JAK2 O60674 1/20 0.42
PRKD3 O94806 1/20 0.42
MAP4K4 O95819 1/20 0.42
PAK4 O96013 1/20 0.42
ABL1 P00519 1/20 0.42
LCK P06239 1/20 0.42
FYN P06241 1/20 0.42
CSF1R P07333 1/20 0.42
RET P07949 1/20 0.42
IGF1R P08069 1/20 0.42
MET P08581 1/20 0.42
PDGFRB P09619 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18174560 0.89 CYP11B1 (0.50) CYP11B1KDM4ELMNAHTTCYP11B2
SCHEMBL18422307 0.88 CYP11B1 (0.50) CYP11B1DHODHLMNACHEK1AURKA
SCHEMBL18174579 0.86 PIK3CA (0.49) DHODHKDM4ELMNACHEK1ALK
SCHEMBL18174609 0.83 SLC2A1 (0.47) CYP11B1DHODHKDM4ELMNAHTT
SCHEMBL18174573 0.83 SLC2A1 (0.49) CYP11B1DHODHKDM4ELMNAHTT
SCHEMBL18174582 0.83 RET (0.46) CYP11B1DHODHKDM4ELMNAHTT
SCHEMBL18174611 0.82 SLC2A1 (0.49) CYP11B1DHODHKDM4ELMNAHTT
SCHEMBL15160968 0.82 SLC2A1 (0.51) CYP11B1DHODHKDM4ELMNAHTT
SCHEMBL13145249 0.81 CYP11B1 (0.50) CYP11B1DHODHKDM4ELMNACHEK1
SCHEMBL15977925 0.81 CYP11B1 (0.53) CYP11B1DHODHKDM4ECHEK1AURKA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9478750-B2 Anthracene derivative and organic electroluminescent element using the same JNC CORPORATION (JP) 2016-10-25 US disclosed
US-9478750-B2 Anthracene derivative and organic electroluminescent element using the same JNC CORPORATION (JP) 2016-10-25 US disclosed