SCHEMBL18174682

SCHEMBL18174682

Cc1cnccc1-c1ccc(-c2c3ccccc3c(-c3ccc(-c4cccnc4)cc3C)c3ccccc23)cc1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC2A1 P11166 1/20 0.52
PIK3CA P42336 1/20 0.45
MKNK1 Q9BUB5 1/20 0.43
MKNK2 Q9HBH9 1/20 0.43
CYP19A1 P11511 3/20 0.42
CYP11B1 P15538 4/20 0.41
CYP17A1 P05093 4/20 0.41
CYP11B2 P19099 3/20 0.41
PDE3B Q13370 1/20 0.41
PDE3A Q14432 1/20 0.41
CHEK1 O14757 2/20 0.40
DYRK1A Q13627 2/20 0.40
DYRK1B Q9Y463 2/20 0.40
AURKA O14965 1/20 0.40
DAPK3 O43293 1/20 0.40
JAK2 O60674 1/20 0.40
PRKD3 O94806 1/20 0.40
MAP4K4 O95819 1/20 0.40
PAK4 O96013 1/20 0.40
ABL1 P00519 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18174681 0.92 SLC2A1 (0.51) SLC2A1PIK3CAMKNK1MKNK2CYP19A1
SCHEMBL18174656 0.90 SLC2A1 (0.49) SLC2A1PIK3CAMKNK1MKNK2CYP19A1
SCHEMBL18174678 0.90 PIK3CA (0.41) SLC2A1PIK3CACYP19A1CYP17A1MAP4K4
SCHEMBL18174716 0.90 PIK3CA (0.47) SLC2A1PIK3CAMKNK1MKNK2CYP19A1
SCHEMBL18174556 0.89 SLC2A1 (0.54) SLC2A1PIK3CAMKNK1MKNK2CYP19A1
SCHEMBL18174778 0.88 CYP19A1 (0.45) SLC2A1PIK3CAMKNK1MKNK2CYP19A1
SCHEMBL18174626 0.85 GRM4 (0.42) SLC2A1PIK3CACYP19A1CYP17A1CHEK1
SCHEMBL18174726 0.85 SLC2A1 (0.47) SLC2A1PIK3CAMKNK1MKNK2CYP19A1
SCHEMBL18174679 0.85 SLC2A1 (0.46) SLC2A1PIK3CAMKNK1MKNK2CYP19A1
SCHEMBL15161035 0.84 SLC2A1 (0.49) SLC2A1PIK3CAMKNK1MKNK2CYP19A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9478750-B2 Anthracene derivative and organic electroluminescent element using the same JNC CORPORATION (JP) 2016-10-25 US disclosed
US-9478750-B2 Anthracene derivative and organic electroluminescent element using the same JNC CORPORATION (JP) 2016-10-25 US disclosed