Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CA | P42336 | 1/20 | 0.47 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.45 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.44 |
| ▸ | CYP11B1 | P15538 | 5/20 | 0.43 |
| ▸ | CYP11B2 | P19099 | 4/20 | 0.43 |
| ▸ | CYP17A1 | P05093 | 3/20 | 0.43 |
| ▸ | MKNK1 | Q9BUB5 | 2/20 | 0.42 |
| ▸ | MKNK2 | Q9HBH9 | 2/20 | 0.42 |
| ▸ | CHEK1 | O14757 | 2/20 | 0.42 |
| ▸ | AURKA | O14965 | 1/20 | 0.42 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.42 |
| ▸ | JAK2 | O60674 | 1/20 | 0.42 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.42 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.42 |
| ▸ | PAK4 | O96013 | 1/20 | 0.42 |
| ▸ | ABL1 | P00519 | 1/20 | 0.42 |
| ▸ | LCK | P06239 | 1/20 | 0.42 |
| ▸ | FYN | P06241 | 1/20 | 0.42 |
| ▸ | CSF1R | P07333 | 1/20 | 0.42 |
| ▸ | RET | P07949 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18174750 | 0.92 | GRM4 (0.43) | CYP19A1CYP17A1CHEK1MAP4K4ABL1 | |
| SCHEMBL18174713 | 0.91 | PIK3CA (0.41) | PIK3CASLC2A1CYP19A1CYP11B1CYP11B2 | |
| SCHEMBL18174753 | 0.91 | PIK3CA (0.45) | PIK3CACYP19A1CYP17A1MKNK1CHEK1 | |
| SCHEMBL18174682 | 0.90 | SLC2A1 (0.52) | PIK3CASLC2A1CYP19A1CYP11B1CYP11B2 | |
| SCHEMBL15161087 | 0.90 | CYP17A1 (0.47) | PIK3CASLC2A1CYP19A1CYP11B1CYP11B2 | |
| SCHEMBL18174681 | 0.90 | SLC2A1 (0.51) | PIK3CASLC2A1CYP19A1CYP11B1CYP11B2 | |
| SCHEMBL18174711 | 0.89 | GRM4 (0.37) | PIK3CASLC2A1CYP19A1CYP11B1CYP11B2 | |
| SCHEMBL15161102 | 0.87 | GRM4 (0.46) | PIK3CACYP19A1CYP11B1CYP17A1CDK8 | |
| SCHEMBL15161084 | 0.87 | CYP17A1 (0.47) | CYP11B1CYP11B2CYP17A1ABL1CYP1A2 | |
| SCHEMBL18174730 | 0.87 | CYP17A1 (0.47) | CYP11B1CYP11B2CYP17A1ABL1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9478750-B2 | Anthracene derivative and organic electroluminescent element using the same | JNC CORPORATION (JP) | 2016-10-25 | — | — | US | disclosed |
| US-9478750-B2 | Anthracene derivative and organic electroluminescent element using the same | JNC CORPORATION (JP) | 2016-10-25 | — | — | US | disclosed |