SCHEMBL18174710

SCHEMBL18174710

Cc1ccc(-c2ccc(-c3c4ccccc4c(-c4ccc(-c5ccncc5)cc4)c4ccccc34)cc2)cn1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
IMPDH2 P12268 1/20 0.45
MAPK1 P28482 1/20 0.41
NOTUM Q6P988 1/20 0.41
HPGDS O60760 1/20 0.40
PDGFRB P09619 1/20 0.40
PDGFRA P16234 1/20 0.40
NPC1 O15118 2/20 0.39
PKM P14618 1/20 0.39
RAB9A P51151 1/20 0.39
MAPK14 Q16539 4/20 0.38
KDR P35968 2/20 0.38
MAPK13 O15264 1/20 0.38
MAPK12 P53778 1/20 0.38
MAPK11 Q15759 1/20 0.38
WNT3A P56704 1/20 0.37
PDK2 Q15119 1/20 0.37
LMNA P02545 1/20 0.37
MAPT P10636 1/20 0.37
PIK3CA P42336 1/20 0.36
HSP90AA1 P07900 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15161061 0.91 PIK3CA (0.40) IMPDH2MAPK1NOTUMPDGFRBPDGFRA
SCHEMBL18174754 0.91 PIK3CA (0.40) IMPDH2MAPK1NOTUMHPGDSPDGFRB
SCHEMBL17532877 0.91 NPC1 (0.44) HPGDSNPC1PKMRAB9AWNT3A
SCHEMBL15161083 0.89 CYP2A6 (0.49) PDGFRBPDGFRAKDR
SCHEMBL18174749 0.88 SLC2A1 (0.39) IMPDH2MAPK1PDGFRBPDGFRAMAPK14
SCHEMBL18174693 0.88 MAPK14 (0.38) IMPDH2MAPK1PDGFRBPDGFRAMAPK14
SCHEMBL18174687 0.86 WNT3A (0.51) WNT3APIK3CA
SCHEMBL30731123 0.86 MAPT (0.50) MAPK1NOTUMHPGDSPDGFRBPDGFRA
SCHEMBL12145549 0.86 MAPT (0.50) MAPK1NOTUMHPGDSPDGFRBPDGFRA
SCHEMBL18174648 0.85 GRM4 (0.41) MAPK1HPGDSNPC1PKMRAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9478750-B2 Anthracene derivative and organic electroluminescent element using the same JNC CORPORATION (JP) 2016-10-25 US disclosed
US-9478750-B2 Anthracene derivative and organic electroluminescent element using the same JNC CORPORATION (JP) 2016-10-25 US disclosed