SCHEMBL18174693

SCHEMBL18174693

Cc1ccc(-c2ccc(-c3c4ccccc4c(-c4ccc(-c5ccncc5)cc4C)c4ccccc34)cc2)cn1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPK14 Q16539 1/20 0.38
PIK3CA P42336 2/20 0.38
MAPK1 P28482 1/20 0.37
SLC2A1 P11166 1/20 0.37
IMPDH2 P12268 2/20 0.37
LRRK2 Q5S007 1/20 0.36
WNT3A P56704 2/20 0.36
NTRK1 P04629 1/20 0.36
PDGFRB P09619 1/20 0.35
PDGFRA P16234 1/20 0.35
FYN P06241 1/20 0.35
KDR P35968 1/20 0.34
CDC7 O00311 1/20 0.34
ROCK2 O75116 1/20 0.34
MAP4K4 O95819 1/20 0.34
PRKACA P17612 1/20 0.34
CDK2 P24941 1/20 0.34
GSK3B P49841 1/20 0.34
CLK4 Q9HAZ1 1/20 0.34
IRAK4 Q9NWZ3 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18174749 0.92 SLC2A1 (0.39) MAPK14PIK3CAMAPK1SLC2A1IMPDH2
SCHEMBL18174679 0.91 SLC2A1 (0.46) PIK3CAMAPK1SLC2A1LRRK2WNT3A
SCHEMBL18174754 0.88 PIK3CA (0.40) MAPK14PIK3CAMAPK1IMPDH2PDGFRB
SCHEMBL18174710 0.88 IMPDH2 (0.45) MAPK14PIK3CAMAPK1IMPDH2WNT3A
SCHEMBL18174662 0.87 DYRK1A (0.43) MAPK14PIK3CAIMPDH2LRRK2WNT3A
SCHEMBL18174557 0.86 MAPK14 (0.43) MAPK14PIK3CAMAPK1IMPDH2LRRK2
SCHEMBL15161061 0.85 PIK3CA (0.40) PIK3CAMAPK1IMPDH2LRRK2WNT3A
SCHEMBL18174708 0.85 WNT3A (0.39) WNT3AKDRIRAK4
SCHEMBL18174652 0.84 PORCN (0.47) PIK3CASLC2A1LRRK2WNT3APDGFRB
SCHEMBL18174714 0.84 DHODH (0.45) MAPK14PIK3CASLC2A1IMPDH2LRRK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9478750-B2 Anthracene derivative and organic electroluminescent element using the same JNC CORPORATION (JP) 2016-10-25 US disclosed
US-9478750-B2 Anthracene derivative and organic electroluminescent element using the same JNC CORPORATION (JP) 2016-10-25 US disclosed