SCHEMBL18174721

SCHEMBL18174721

Cc1ccc(-c2ccc(-c3c4ccccc4c(-c4ccc(-c5cccc(C)n5)cc4)c4ccccc34)cc2)cn1

nearest known ligand 0.46

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
CYP2A6 P11509 1/20 0.46
CCR1 P32246 1/20 0.43
CCR8 P51685 1/20 0.43
TGFBR1 P36897 11/20 0.39
NPC1 O15118 1/20 0.38
PKM P14618 1/20 0.38
RAB9A P51151 1/20 0.38
GRM5 P41594 1/20 0.38
MAPK14 Q16539 2/20 0.37
PDK2 Q15119 1/20 0.36
METAP2 P50579 1/20 0.36
BRS3 P32247 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16189084 0.87 CCR1 (0.56) CYP2A6CCR1CCR8TGFBR1RAB9A
SCHEMBL17532877 0.86 NPC1 (0.44) CYP2A6NPC1PKMRAB9APDK2
SCHEMBL17532887 0.84 CCR1 (0.37) CYP2A6CCR1CCR8TGFBR1NPC1
SCHEMBL18174690 0.84 CYP2A6 (0.44) CYP2A6CCR1CCR8NPC1PKM
SCHEMBL3421947 0.82 CYP2A6 (0.65) CYP2A6CCR1CCR8TGFBR1NPC1
SCHEMBL30146674 0.82 CYP2A6 (0.65) CYP2A6CCR1CCR8TGFBR1NPC1
SCHEMBL16189077 0.80 CCR1 (0.52) CYP2A6CCR1CCR8TGFBR1GRM5
SCHEMBL17532878 0.80 CCR1 (0.47) CYP2A6CCR1CCR8TGFBR1RAB9A
SCHEMBL16189031 0.80 PSD (0.39) NPC1PKMRAB9APDK2
SCHEMBL18174658 0.80 TGFBR1 (0.44) CYP2A6CCR1CCR8TGFBR1MAPK14

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9478750-B2 Anthracene derivative and organic electroluminescent element using the same JNC CORPORATION (JP) 2016-10-25 US disclosed
US-9478750-B2 Anthracene derivative and organic electroluminescent element using the same JNC CORPORATION (JP) 2016-10-25 US disclosed