SCHEMBL18174690

SCHEMBL18174690

Cc1ccc(-c2ccc(-c3c4ccccc4c(-c4ccc(-c5ccccn5)cc4)c4ccccc34)cc2)cn1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2A6 P11509 1/20 0.44
GRM5 P41594 1/20 0.41
CYP1A2 P05177 2/20 0.41
CYP2D6 P10635 1/20 0.41
CYP19A1 P11511 1/20 0.41
CYP2C9 P11712 1/20 0.41
CYP2C19 P33261 1/20 0.41
DHODH Q02127 1/20 0.39
AURKA O14965 1/20 0.38
CNR2 P34972 1/20 0.38
KDM4E B2RXH2 1/20 0.38
LMNA P02545 1/20 0.38
POLB P06746 1/20 0.38
CCR1 P32246 1/20 0.38
CCR5 P51681 1/20 0.38
CCR8 P51685 1/20 0.38
METAP1 P53582 1/20 0.38
BLM P54132 1/20 0.38
HIF1A Q16665 1/20 0.38
DOHH Q9BU89 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17055549 0.91 CYP2A6 (0.52) CYP2A6GRM5CYP1A2CYP2D6CYP19A1
SCHEMBL15161074 0.90 CYP2A6 (0.42) CYP2A6GRM5DHODHWNT3AKDR
SCHEMBL17532877 0.87 NPC1 (0.44) CYP2A6CYP1A2WNT3AHPGDSPDE10A
SCHEMBL18174708 0.87 WNT3A (0.39) CYP2A6GRM5DHODHCNR2KDM4E
SCHEMBL18174701 0.85 WNT3A (0.37) CYP2A6GRM5CNR2KDM4EMETAP1
SCHEMBL18174680 0.84 CYP2A6 (0.50) CYP2A6GRM5KDM4ELMNACCR1
SCHEMBL18174721 0.84 CYP2A6 (0.46) CYP2A6GRM5CCR1CCR8NPC1
SCHEMBL18174699 0.84 CYP3A4 (0.46) CYP2A6DHODHKDM4ELMNACCR1
SCHEMBL2083184 0.84 CYP2A6 (0.60) CYP2A6GRM5CYP1A2CYP2D6CYP19A1
SCHEMBL29777054 0.84 CYP2A6 (0.60) CYP2A6GRM5CYP1A2CYP2D6CYP19A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9478750-B2 Anthracene derivative and organic electroluminescent element using the same JNC CORPORATION (JP) 2016-10-25 US disclosed
US-9478750-B2 Anthracene derivative and organic electroluminescent element using the same JNC CORPORATION (JP) 2016-10-25 US disclosed