SCHEMBL18174723

SCHEMBL18174723

Cc1cncc(-c2ccc(-c3c4ccccc4c(-c4cccc(-c5ccccn5)c4)c4ccccc34)cc2)c1

nearest known ligand 0.43

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
CYP2A6 P11509 2/20 0.43
TGFBR1 P36897 1/20 0.40
GRM5 P41594 5/20 0.39
HRH3 Q9Y5N1 1/20 0.38
DCTPP1 Q9H773 1/20 0.37
IRAK4 Q9NWZ3 1/20 0.37
CYP3A4 P08684 1/20 0.37
CYP11B1 P15538 1/20 0.37
CYP11B2 P19099 1/20 0.37
RAF1 P04049 1/20 0.35
BCHE P06276 1/20 0.35
ACHE P22303 1/20 0.35
PKMYT1 Q99640 1/20 0.35
SCN5A Q14524 1/20 0.35
SCN9A Q15858 1/20 0.35
PDE2A O00408 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15160977 0.92 CYP2A6 (0.44) CYP2A6TGFBR1GRM5CYP3A4CYP11B1
SCHEMBL15161059 0.89 CYP2A6 (0.51) CYP2A6TGFBR1DCTPP1BCHEACHE
SCHEMBL15161049 0.88 CYP3A4 (0.47) CYP2A6CYP3A4CYP11B1CYP11B2
SCHEMBL18174704 0.87 RAF1 (0.38) CYP2A6TGFBR1GRM5DCTPP1IRAK4
SCHEMBL15161047 0.87 CYP11B2 (0.43) CYP2A6CYP11B1CYP11B2ACHE
SCHEMBL18174702 0.85 RAF1 (0.36) CYP2A6TGFBR1GRM5DCTPP1RAF1
SCHEMBL15161053 0.85 CYP2A6 (0.47) CYP2A6TGFBR1CYP11B1CYP11B2
SCHEMBL10030095 0.84 CYP2A6 (0.59) CYP2A6GRM5HRH3DCTPP1CYP3A4
SCHEMBL15160987 0.84 CYP2A6 (0.41) CYP2A6CYP11B1CYP11B2
SCHEMBL10032181 0.83 GRM5 (0.44) CYP2A6TGFBR1GRM5DCTPP1IRAK4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9478750-B2 Anthracene derivative and organic electroluminescent element using the same JNC CORPORATION (JP) 2016-10-25 US disclosed
US-9478750-B2 Anthracene derivative and organic electroluminescent element using the same JNC CORPORATION (JP) 2016-10-25 US disclosed