SCHEMBL18174748

SCHEMBL18174748

Cc1cccc(-c2ccc(-c3c4ccccc4c(-c4ccc(-c5cccnc5C)cc4)c4ccccc34)cc2)n1

nearest known ligand 0.50

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
DHODH Q02127 1/20 0.50
TGFBR1 P36897 15/20 0.45
CYP2A6 P11509 1/20 0.43
MKNK1 Q9BUB5 1/20 0.43
MKNK2 Q9HBH9 1/20 0.43
MAPK14 Q16539 2/20 0.40
CCR1 P32246 1/20 0.40
CCR8 P51685 1/20 0.40
ENPP3 O14638 1/20 0.38
ENPP1 P22413 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15161065 0.92 DHODH (0.46) DHODHTGFBR1CYP2A6MKNK1MKNK2
SCHEMBL18174715 0.86 DHODH (0.51) DHODHTGFBR1CYP2A6MKNK1MKNK2
SCHEMBL16189088 0.85 MKNK1 (0.54) DHODHCYP2A6MKNK1MKNK2CCR1
SCHEMBL16189084 0.84 CCR1 (0.56) TGFBR1CYP2A6MAPK14CCR1CCR8
SCHEMBL9612930 0.82 DHODH (0.50) DHODHCYP2A6MKNK1MKNK2CCR1
SCHEMBL18174721 0.79 CYP2A6 (0.46) TGFBR1CYP2A6MAPK14CCR1CCR8
SCHEMBL9612955 0.79 DHODH (0.47) DHODHCYP2A6MKNK1MKNK2MAPK14
SCHEMBL18174691 0.79 MKNK1 (0.46) DHODHMKNK1MKNK2
SCHEMBL15161030 0.79 MKNK1 (0.48) DHODHMKNK1MKNK2MAPK14
SCHEMBL18174695 0.78 DHODH (0.50) DHODHTGFBR1CYP2A6MKNK1MKNK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9478750-B2 Anthracene derivative and organic electroluminescent element using the same JNC CORPORATION (JP) 2016-10-25 US disclosed
US-9478750-B2 Anthracene derivative and organic electroluminescent element using the same JNC CORPORATION (JP) 2016-10-25 US disclosed