SCHEMBL9612955

SCHEMBL9612955

Cc1ncccc1-c1ccc(-c2c3ccccc3c(-c3cccc4c(C)cccc34)c3ccccc23)cc1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DHODH Q02127 3/20 0.47
MKNK1 Q9BUB5 1/20 0.46
MKNK2 Q9HBH9 1/20 0.46
CYP2A6 P11509 3/20 0.38
CYP1A2 P05177 2/20 0.38
MAPT P10636 1/20 0.37
THRB P10828 1/20 0.37
ELANE P08246 1/20 0.36
CA12 O43570 1/20 0.36
CA1 P00915 1/20 0.36
CA2 P00918 1/20 0.36
CA9 Q16790 1/20 0.36
PRMT5 O14744 1/20 0.36
WDR77 Q9BQA1 1/20 0.36
COMT P21964 1/20 0.35
PTGS1 P23219 2/20 0.35
PTGS2 P35354 2/20 0.35
VHL P40337 1/20 0.35
ALDH1A1 P00352 1/20 0.34
CCR1 P32246 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9612969 0.94 DHODH (0.47) DHODHMKNK1MKNK2CYP2A6CYP1A2
SCHEMBL16189088 0.89 MKNK1 (0.54) DHODHMKNK1MKNK2CYP2A6MAPT
SCHEMBL9612930 0.88 DHODH (0.50) DHODHMKNK1MKNK2CYP2A6MAPT
SCHEMBL18174709 0.85 MKNK1 (0.46) DHODHMKNK1MKNK2CYP2A6MAPT
SCHEMBL9612807 0.85 PTGS2 (0.50) DHODHCYP2A6CYP1A2PTGS1PTGS2
SCHEMBL18174795 0.84 DHODH (0.46) DHODHMKNK1MKNK2CA12CA1
SCHEMBL15161030 0.82 MKNK1 (0.48) DHODHMKNK1MKNK2CA12CA1
SCHEMBL18174786 0.82 DHODH (0.47) DHODHMKNK1MKNK2CA12CA1
SCHEMBL18174797 0.81 CYP17A1 (0.45) DHODHMKNK1MKNK2CYP1A2PTGS2
SCHEMBL18174794 0.81 DHODH (0.42) DHODHMKNK1MKNK2CYP1A2CA12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2012070535-A1 ELECTRON TRANSPORT MATERIAL, AND ORGANIC ELECTROLUMINESCENT ELEMENT USING SAME JNC株式会社 (JP) 2012-05-31 WO disclosed