SCHEMBL18174768

SCHEMBL18174768

Cc1cc(-c2ccc(-c3c4ccccc4c(-c4ccc(-c5cccnc5C)c5ccccc45)c4ccccc34)cc2)ccn1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PDK2 Q15119 1/20 0.43
MAP4K4 O95819 2/20 0.41
MKNK2 Q9HBH9 2/20 0.41
CDC7 O00311 1/20 0.41
ROCK2 O75116 1/20 0.41
CDK2 P24941 1/20 0.41
GSK3B P49841 1/20 0.41
CLK4 Q9HAZ1 1/20 0.41
IRAK4 Q9NWZ3 1/20 0.41
DYRK1A Q13627 1/20 0.41
DHODH Q02127 1/20 0.40
WNT3A P56704 3/20 0.38
PSEN1 P49768 2/20 0.38
PSEN2 P49810 2/20 0.38
APH1B Q8WW43 2/20 0.38
NCSTN Q92542 2/20 0.38
APH1A Q96BI3 2/20 0.38
PSENEN Q9NZ42 2/20 0.38
CYP3A4 P08684 1/20 0.38
CYP2D6 P10635 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18174670 0.91 DHODH (0.45) PDK2MAP4K4MKNK2CDC7ROCK2
SCHEMBL18174796 0.90 DHODH (0.46) PDK2MAP4K4MKNK2CDC7ROCK2
SCHEMBL18174743 0.86 DYRK1A (0.47) PDK2MAP4K4MKNK2CDC7ROCK2
SCHEMBL18174733 0.86 LRRK2 (0.41) PDK2MAP4K4MKNK2CDC7ROCK2
SCHEMBL15161058 0.85 DHODH (0.43) PDK2MAP4K4MKNK2CDC7ROCK2
SCHEMBL9612984 0.84 DYRK1A (0.45) PDK2MAP4K4MKNK2CDC7ROCK2
SCHEMBL10016748 0.83 DHODH (0.44) MKNK2DHODHTDO2MKNK1
SCHEMBL16189065 0.83 DYRK1A (0.56) PDK2MAP4K4MKNK2CDC7ROCK2
SCHEMBL18174784 0.83 WNT3A (0.44) PDK2MAP4K4MKNK2CDC7ROCK2
SCHEMBL9612986 0.83 DYRK1A (0.44) PDK2MAP4K4MKNK2CDC7ROCK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9478750-B2 Anthracene derivative and organic electroluminescent element using the same JNC CORPORATION (JP) 2016-10-25 US disclosed
US-9478750-B2 Anthracene derivative and organic electroluminescent element using the same JNC CORPORATION (JP) 2016-10-25 US disclosed