SCHEMBL18174796

SCHEMBL18174796

Cc1cc(-c2ccc(-c3c4ccccc4c(-c4ccc(-c5cccnc5C)cc4)c4ccccc34)c3ccccc23)ccn1

nearest known ligand 0.46

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
DHODH Q02127 1/20 0.46
MKNK2 Q9HBH9 2/20 0.41
MKNK1 Q9BUB5 1/20 0.41
PDK2 Q15119 1/20 0.40
MAP4K4 O95819 2/20 0.39
CDC7 O00311 1/20 0.39
ROCK2 O75116 1/20 0.39
CDK2 P24941 1/20 0.39
GSK3B P49841 1/20 0.39
CLK4 Q9HAZ1 1/20 0.39
IRAK4 Q9NWZ3 1/20 0.39
TDO2 P48775 2/20 0.38
PRMT5 O14744 1/20 0.37
WDR77 Q9BQA1 1/20 0.37
COMT P21964 1/20 0.37
LRRK2 Q5S007 1/20 0.36
DYRK1A Q13627 2/20 0.35
NFATC1 O95644 1/20 0.35
GLO1 Q04760 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18174670 0.91 DHODH (0.45) DHODHMKNK2MKNK1PDK2MAP4K4
SCHEMBL18174768 0.90 PDK2 (0.43) DHODHMKNK2MKNK1PDK2MAP4K4
SCHEMBL15161058 0.87 DHODH (0.43) DHODHMKNK2MKNK1PDK2MAP4K4
SCHEMBL18174795 0.87 DHODH (0.46) DHODHMKNK2MKNK1COMTGLO1
SCHEMBL18174743 0.86 DYRK1A (0.47) MKNK2PDK2MAP4K4CDC7ROCK2
SCHEMBL18174733 0.86 LRRK2 (0.41) DHODHMKNK2MKNK1PDK2MAP4K4
SCHEMBL18174786 0.84 DHODH (0.47) DHODHMKNK2MKNK1PDK2TDO2
SCHEMBL16189088 0.83 MKNK1 (0.54) DHODHMKNK2MKNK1TDO2PRMT5
SCHEMBL9613009 0.83 DHODH (0.48) DHODHMKNK2MKNK1MAP4K4CDC7
SCHEMBL18174762 0.83 PIK3CA (0.49) MKNK2PDK2MAP4K4CDC7ROCK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9478750-B2 Anthracene derivative and organic electroluminescent element using the same JNC CORPORATION (JP) 2016-10-25 US disclosed
US-9478750-B2 Anthracene derivative and organic electroluminescent element using the same JNC CORPORATION (JP) 2016-10-25 US disclosed