SCHEMBL18174775

SCHEMBL18174775

Cc1cncc(-c2ccc(-c3c4ccccc4c(-c4ccc(-c5ccncc5C)c5ccccc45)c4ccccc34)cc2)c1

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GRM4 Q14833 1/20 0.35
CYP2A6 P11509 3/20 0.35
CYP19A1 P11511 1/20 0.34
S1PR1 P21453 2/20 0.34
S1PR3 Q99500 2/20 0.34
DHODH Q02127 1/20 0.34
CYP17A1 P05093 2/20 0.33
CYP11B1 P15538 2/20 0.33
CYP11B2 P19099 1/20 0.33
PDE3B Q13370 1/20 0.33
PDE3A Q14432 1/20 0.33
CDK7 P50613 1/20 0.32
CYP1A2 P05177 1/20 0.32
METAP2 P50579 1/20 0.32
PIK3C3 Q8NEB9 1/20 0.32
CCNC P24863 1/20 0.32
CDK8 P49336 1/20 0.32
TDO2 P48775 1/20 0.32
CYP46A1 Q9Y6A2 1/20 0.31
GBA1 P04062 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18174627 0.91 GRM4 (0.40) GRM4CYP2A6CYP19A1S1PR1S1PR3
SCHEMBL18174791 0.90 DHODH (0.41) CYP2A6DHODHCYP17A1CYP11B1CYP11B2
SCHEMBL18174760 0.90 GRM4 (0.38) GRM4CYP2A6CYP19A1S1PR1S1PR3
SCHEMBL15161052 0.86 RPS6KA3 (0.38) GRM4CYP2A6CYP19A1S1PR1S1PR3
SCHEMBL18174777 0.86 CYP2A6 (0.40) CYP2A6S1PR1S1PR3DHODHCYP11B1
SCHEMBL18174776 0.85 GRM4 (0.43) GRM4CYP19A1S1PR1S1PR3DHODH
SCHEMBL18174764 0.85 CYP2A6 (0.41) CYP2A6S1PR1S1PR3CYP11B1CYP11B2
SCHEMBL15161110 0.85 CYP11B1 (0.44) CYP2A6DHODHCYP11B1CYP11B2
SCHEMBL18174711 0.84 GRM4 (0.37) GRM4CYP2A6CYP19A1S1PR1S1PR3
SCHEMBL18174672 0.84 CYP2A6 (0.38) CYP2A6S1PR1S1PR3CYP11B1CYP11B2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9478750-B2 Anthracene derivative and organic electroluminescent element using the same JNC CORPORATION (JP) 2016-10-25 US disclosed
US-9478750-B2 Anthracene derivative and organic electroluminescent element using the same JNC CORPORATION (JP) 2016-10-25 US disclosed