SCHEMBL18174791

SCHEMBL18174791

Cc1cncc(-c2ccc(-c3c4ccccc4c(-c4ccc(-c5cnccc5C)c5ccccc45)c4ccccc34)cc2)c1

nearest known ligand 0.41

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
DHODH Q02127 1/20 0.41
CYP17A1 P05093 12/20 0.40
CYP1A2 P05177 9/20 0.40
CYP11B1 P15538 2/20 0.36
CYP11B2 P19099 2/20 0.36
PTGS2 P35354 1/20 0.35
CYP2A6 P11509 3/20 0.35
ABL1 P00519 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15160916 0.91 DHODH (0.46) DHODHCYP17A1CYP1A2CYP11B1CYP11B2
SCHEMBL18174789 0.90 DHODH (0.46) DHODHCYP17A1CYP1A2CYP11B1CYP11B2
SCHEMBL18174775 0.90 GRM4 (0.35) DHODHCYP17A1CYP1A2CYP11B1CYP11B2
SCHEMBL15161069 0.86 CYP17A1 (0.42) DHODHCYP17A1CYP1A2CYP11B1CYP11B2
SCHEMBL18174777 0.86 CYP2A6 (0.40) DHODHCYP11B1CYP11B2CYP2A6
SCHEMBL18174764 0.85 CYP2A6 (0.41) CYP11B1CYP11B2PTGS2CYP2A6
SCHEMBL18174788 0.85 DHODH (0.50) DHODHCYP17A1CYP1A2CYP11B1CYP11B2
SCHEMBL15161110 0.85 CYP11B1 (0.44) DHODHCYP11B1CYP11B2PTGS2CYP2A6
SCHEMBL18174735 0.84 CYP17A1 (0.44) DHODHCYP17A1CYP1A2CYP11B1CYP11B2
SCHEMBL10017304 0.84 CYP17A1 (0.53) DHODHCYP17A1CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9478750-B2 Anthracene derivative and organic electroluminescent element using the same JNC CORPORATION (JP) 2016-10-25 US disclosed
US-9478750-B2 Anthracene derivative and organic electroluminescent element using the same JNC CORPORATION (JP) 2016-10-25 US disclosed