SCHEMBL18174786

SCHEMBL18174786

Cc1ccc(-c2ccc(-c3c4ccccc4c(-c4ccc(-c5cccnc5C)cc4)c4ccccc34)c3ccccc23)cn1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DHODH Q02127 4/20 0.47
MKNK1 Q9BUB5 1/20 0.46
MKNK2 Q9HBH9 1/20 0.46
COMT P21964 1/20 0.42
PDK2 Q15119 1/20 0.40
PTGS2 P35354 3/20 0.39
ABL1 P00519 1/20 0.37
TDO2 P48775 2/20 0.36
MAPK10 P53779 1/20 0.36
CKS1B P61024 1/20 0.35
GLO1 Q04760 1/20 0.35
SKP2 Q13309 1/20 0.35
PTGS1 P23219 1/20 0.35
HPGDS O60760 1/20 0.34
CA12 O43570 1/20 0.34
CA1 P00915 1/20 0.34
CA2 P00918 1/20 0.34
CA9 Q16790 1/20 0.34
MAOA P21397 1/20 0.34
MAOB P27338 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18174691 0.90 MKNK1 (0.46) DHODHMKNK1MKNK2COMTPDK2
SCHEMBL18174774 0.88 PTGS2 (0.47) DHODHMKNK1MKNK2COMTPTGS2
SCHEMBL18174795 0.86 DHODH (0.46) DHODHMKNK1MKNK2COMTCKS1B
SCHEMBL18174772 0.86 PDK2 (0.42) DHODHCOMTPDK2PTGS2ABL1
SCHEMBL16189088 0.85 MKNK1 (0.54) DHODHMKNK1MKNK2COMTPTGS2
SCHEMBL9612969 0.85 DHODH (0.47) DHODHMKNK1MKNK2COMTPTGS2
SCHEMBL15161055 0.84 DHODH (0.43) DHODHMKNK1MKNK2PDK2PTGS2
SCHEMBL18174796 0.84 DHODH (0.46) DHODHMKNK1MKNK2COMTPDK2
SCHEMBL18174754 0.82 PIK3CA (0.40) COMTPDK2MAPK10CKS1BSKP2
SCHEMBL18174765 0.82 DHODH (0.44) DHODHMKNK1MKNK2COMTPTGS2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9478750-B2 Anthracene derivative and organic electroluminescent element using the same JNC CORPORATION (JP) 2016-10-25 US disclosed
US-9478750-B2 Anthracene derivative and organic electroluminescent element using the same JNC CORPORATION (JP) 2016-10-25 US disclosed