SCHEMBL18174860

SCHEMBL18174860

Cc1ccc(Cc2cc(C)cc(Cc3ccc(O)cc3O)c2O)c(O)c1

nearest known ligand 0.66

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
AMY1A P0DUB6 1/20 0.66
ALOX5 P09917 3/20 0.47
TYR P14679 6/20 0.47
CYP2C9 P11712 1/20 0.46
CYP2C19 P33261 1/20 0.46
SMN1; SMN2 Q16637 1/20 0.46
HIF1A Q16665 1/20 0.46
MEN1 O00255 2/20 0.45
MAPT P10636 2/20 0.45
KMT2A Q03164 2/20 0.45
HSPA5 P11021 1/20 0.43
TP53 P04637 1/20 0.41
CYP3A4 P08684 1/20 0.41
ALOX15 P16050 1/20 0.41
TSHR P16473 1/20 0.41
HTT P42858 1/20 0.41
TDP1 Q9NUW8 1/20 0.41
TRPA1 O75762 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30703618 0.95 AMY1A (0.61) AMY1AALOX5TYRCYP2C9CYP2C19
SCHEMBL4055159 0.95 AMY1A (0.61) AMY1AALOX5TYRCYP2C9CYP2C19
SCHEMBL4059100 0.95 AMY1A (0.61) AMY1AALOX5TYRCYP2C9CYP2C19
SCHEMBL4004589 0.95 AMY1A (0.61) AMY1AALOX5TYRCYP2C9CYP2C19
SCHEMBL19621170 0.93 AMY1A (0.75) AMY1AALOX5CYP2C9CYP2C19SMN1; SMN2
SCHEMBL14462755 0.88 AMY1A (0.54) AMY1AALOX5TYRCYP2C9CYP2C19
SCHEMBL21096824 0.87 AMY1A (0.57) AMY1AALOX5TYRCYP2C9CYP2C19
SCHEMBL22500133 0.86 AMY1A (0.51) AMY1AALOX5TYRCYP2C9CYP2C19
SCHEMBL8706270 0.86 AMY1A (0.65) AMY1AALOX5TYRSMN1; SMN2HIF1A
SCHEMBL17340631 0.84 AMY1A (0.50) AMY1AALOX5TYRCYP2C9CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9477148-B1 Polymer, method for preparing the same, and a photosensitive resin composition thereof INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) 2016-10-25 US disclosed