Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN1 | Q05586 | 4/20 | 0.47 |
| ▸ | GRIN2A | Q12879 | 4/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.47 |
| ▸ | SLC22A1 | O15245 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.47 |
| ▸ | SIGMAR1 | Q99720 | 6/20 | 0.47 |
| ▸ | GRIN2D | O15399 | 3/20 | 0.47 |
| ▸ | GRIN3B | O60391 | 3/20 | 0.47 |
| ▸ | GRIN2B | Q13224 | 3/20 | 0.47 |
| ▸ | GRIN2C | Q14957 | 3/20 | 0.47 |
| ▸ | GRIN3A | Q8TCU5 | 3/20 | 0.47 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.47 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.47 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.47 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.47 |
| ▸ | TACR1 | P25103 | 1/20 | 0.47 |
| ▸ | HTR2A | P28223 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16015668 | 0.91 | GRIN1 (0.46) | GRIN1GRIN2ACYP2D6SLC22A1TSHR | |
| SCHEMBL22945773 | 0.91 | GRIN1 (0.46) | GRIN1GRIN2ACYP2D6SLC22A1TSHR | |
| SCHEMBL23072577 | 0.88 | GRIN1 (0.43) | GRIN1GRIN2ACYP2D6SLC22A1TSHR | |
| SCHEMBL23072574 | 0.87 | GRIN1 (0.39) | GRIN1GRIN2ACYP2D6SLC22A1TSHR | |
| SCHEMBL25906877 | 0.86 | GRIN1 (0.43) | GRIN1GRIN2ACYP2D6SLC22A1TSHR | |
| SCHEMBL23329761 | 0.85 | GRIN1 (0.41) | GRIN1GRIN2ACYP2D6SLC22A1TSHR | |
| SCHEMBL11703723 | 0.82 | SIGMAR1 (0.44) | GRIN1GRIN2ACYP2D6SLC22A1TSHR | |
| SCHEMBL11703721 | 0.82 | SIGMAR1 (0.44) | GRIN1GRIN2ACYP2D6SLC22A1TSHR | |
| SCHEMBL26085140 | 0.82 | OPRM1 (0.34) | GRIN1GRIN2ACYP2D6SLC22A1TSHR | |
| SCHEMBL23329631 | 0.81 | KCNA5 (0.39) | GRIN1GRIN2ACYP2D6SLC22A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9474731-B1 | Compositions and methods for increasing the metabolic lifetime of dextromethorphan and related pharmacodynamic effects | ANTECIP BIOVENTURES II LLC (US) | 2016-10-25 | — | — | US | disclosed |