Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | SSTR4 | P31391 | 4/20 | 0.38 |
| ▸ | SSTR1 | P30872 | 1/20 | 0.35 |
| ▸ | AR | P10275 | 6/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.33 |
| ▸ | PPARG | P37231 | 1/20 | 0.33 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.33 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.33 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | EZH2 | Q15910 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18174935 | 0.83 | CYP2C9 (0.56) | CYP2C9SSTR4SSTR1ARALDH1A1 | |
| SCHEMBL18174932 | 0.76 | ALDH1A1 (0.46) | SSTR4ARALDH1A1HTTNPSR1 | |
| SCHEMBL13476058 | 0.76 | ALDH1A1 (0.46) | CYP2C9ALDH1A1HTTNPSR1KMT2A | |
| SCHEMBL13476059 | 0.75 | NPSR1 (0.46) | SSTR4ALDH1A1HTTNPSR1KMT2A | |
| SCHEMBL618611 | 0.73 | ALDH1A1 (0.43) | SSTR4ALDH1A1HTTNPSR1KMT2A | |
| SCHEMBL2416326 | 0.70 | ALDH1A1 (0.45) | ALDH1A1HTTHPGDKMT2AMAPT | |
| SCHEMBL621268 | 0.70 | KMT2A (0.43) | SSTR4SSTR1ALDH1A1HTTHPGD | |
| SCHEMBL621577 | 0.70 | ALDH1A1 (0.43) | ALDH1A1HTTNPSR1MRGPRX4KMT2A | |
| SCHEMBL16479679 | 0.69 | CYP2C9 (0.48) | CYP2C9SSTR4SSTR1ARMRGPRX4 | |
| SCHEMBL617944 | 0.69 | CYP2C9 (0.48) | CYP2C9SSTR4ARALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3085699-A2 | PROCESSES AND INTERMEDIATES FOR MAKING SWEET TASTE ENHANCERS | Senomyx, Inc. (US) | 2016-10-26 | — | — | EP | disclosed |