Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 2/20 | 0.56 |
| ▸ | SSTR4 | P31391 | 4/20 | 0.41 |
| ▸ | DGAT1 | O75907 | 3/20 | 0.40 |
| ▸ | PPARG | P37231 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | TTR | P02766 | 1/20 | 0.40 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.40 |
| ▸ | HTR2B | P41595 | 1/20 | 0.40 |
| ▸ | PPARA | Q07869 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | SLCO1B3 | Q9NPD5 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | CISD1 | Q9NZ45 | 1/20 | 0.40 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.40 |
| ▸ | SSTR1 | P30872 | 1/20 | 0.39 |
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.38 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL617944 | 0.85 | CYP2C9 (0.48) | CYP2C9SSTR4DGAT1PPARGCYP1A2 | |
| SCHEMBL16479679 | 0.85 | CYP2C9 (0.48) | CYP2C9SSTR4DGAT1SSTR1MRGPRX4 | |
| SCHEMBL18174934 | 0.83 | CYP2C9 (0.41) | CYP2C9SSTR4PPARGSSTR1MRGPRX4 | |
| SCHEMBL13476058 | 0.81 | ALDH1A1 (0.46) | CYP2C9TSHRTDP1ALDH1A1NPSR1 | |
| SCHEMBL30783156 | 0.81 | SSTR4 (0.59) | CYP2C9SSTR4DGAT1TSHRHTR2B | |
| SCHEMBL21749098 | 0.81 | SSTR4 (0.59) | CYP2C9SSTR4DGAT1TSHRHTR2B | |
| SCHEMBL5850317 | 0.81 | CYP2C9 (0.67) | CYP2C9SSTR4PPARGCYP1A2TTR | |
| SCHEMBL16951877 | 0.74 | CYP1A2 (0.43) | CYP1A2SMN1; SMN2TDP1HPGDALDH1A1 | |
| SCHEMBL5491840 | 0.73 | MRGPRX4 (0.45) | TSHRTDP1MRGPRX4HPGDALDH1A1 | |
| SCHEMBL12219488 | 0.73 | SSTR4 (0.40) | CYP2C9SSTR4DGAT1TSHRSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3085699-A2 | PROCESSES AND INTERMEDIATES FOR MAKING SWEET TASTE ENHANCERS | Senomyx, Inc. (US) | 2016-10-26 | — | — | EP | disclosed |