Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK2 | P24941 | 7/20 | 0.40 |
| ▸ | CCNE1 | P24864 | 6/20 | 0.40 |
| ▸ | CDK5 | Q00535 | 6/20 | 0.40 |
| ▸ | FDPS | P14324 | 1/20 | 0.38 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | CDK1 | P06493 | 1/20 | 0.36 |
| ▸ | CDK4 | P11802 | 1/20 | 0.36 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.36 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.36 |
| ▸ | CCND1 | P24385 | 1/20 | 0.36 |
| ▸ | CDK7 | P50613 | 1/20 | 0.36 |
| ▸ | CDK9 | P50750 | 1/20 | 0.36 |
| ▸ | CCNH | P51946 | 1/20 | 0.36 |
| ▸ | MNAT1 | P51948 | 1/20 | 0.36 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | SLC5A2 | P31639 | 1/20 | 0.33 |
| ▸ | PSEN1 | P49768 | 3/20 | 0.30 |
| ▸ | PSEN2 | P49810 | 3/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2818339 | 0.81 | CDK2 (0.41) | CDK2CCNE1CDK5FDPSCCNT1 | |
| SCHEMBL13533948 | 0.78 | CDK2 (0.39) | CDK2CCNE1CDK5FDPSCCNT1 | |
| SCHEMBL23558952 | 0.76 | CCNE1 (0.38) | CDK2CCNE1CDK5FDPSCCNT1 | |
| SCHEMBL12394764 | 0.76 | CCNE1 (0.38) | CDK2CCNE1CDK5FDPSCCNT1 | |
| SCHEMBL14425148 | 0.76 | CCNE1 (0.38) | CDK2CCNE1CDK5FDPSCCNT1 | |
| SCHEMBL16018754 | 0.73 | SLC5A2 (0.36) | CDK2CCNE1CDK5CCNT1ALDH1A1 | |
| SCHEMBL2818612 | 0.73 | ALDH1A1 (0.40) | CDK2CCNE1CDK5FDPSCCNT1 | |
| SCHEMBL19220560 | 0.72 | SLC5A2 (0.35) | CDK2CCNE1CDK5FDPSCCNT1 | |
| SCHEMBL23208145 | 0.72 | CCNE1 (0.50) | CDK2CCNE1CDK5CCNT1ALDH1A1 | |
| SCHEMBL13748159 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3085695-A1 | SUBSTITUTED TRIAZINONE COMPOUND AND T-TYPE CALCIUM CHANNEL INHIBITOR | Nissan Chemical Industries, Ltd. (JP) | 2016-10-26 | — | — | EP | disclosed |