Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | CCNE1 | P24864 | 2/20 | 0.36 |
| ▸ | CDK2 | P24941 | 2/20 | 0.36 |
| ▸ | CDK5 | Q00535 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.34 |
| ▸ | RAB9A | P51151 | 3/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | FDPS | P14324 | 1/20 | 0.34 |
| ▸ | PSEN1 | P49768 | 2/20 | 0.33 |
| ▸ | PSEN2 | P49810 | 2/20 | 0.33 |
| ▸ | APH1B | Q8WW43 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13533948 | 0.87 | CDK2 (0.39) | ALDH1A1CCNE1CDK2CDK5SMN1; SMN2 | |
| SCHEMBL22926088 | 0.83 | ALDH1A1 (0.39) | ALDH1A1KDM4EPSEN1PSEN2APH1B | |
| SCHEMBL12417805 | 0.82 | CCNE1 (0.36) | ALDH1A1CCNE1CDK2CDK5SMN1; SMN2 | |
| SCHEMBL21240710 | 0.79 | FDPS (0.35) | ALDH1A1FDPSPSEN1PSEN2APH1B | |
| SCHEMBL2818339 | 0.79 | CDK2 (0.41) | ALDH1A1CCNE1CDK2CDK5SMN1; SMN2 | |
| SCHEMBL12394764 | 0.78 | CCNE1 (0.38) | ALDH1A1CCNE1CDK2CDK5SMN1; SMN2 | |
| SCHEMBL5888997 | 0.76 | CCNE1 (0.43) | ALDH1A1TDP1L3MBTL1CCNE1CDK2 | |
| SCHEMBL2820592 | 0.76 | ALDH1A1 (0.43) | ALDH1A1TDP1L3MBTL1SMN1; SMN2RAB9A | |
| SCHEMBL2821023 | 0.74 | ALDH1A1 (0.46) | ALDH1A1TDP1L3MBTL1CCNE1CDK2 | |
| SCHEMBL18174959 | 0.73 | CDK2 (0.40) | ALDH1A1CCNE1CDK2CDK5SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100240890-A1 | Novel benzamidine derivatives, process for the preparation thereof and pharmaceutical composition comprising the same | DONG WHA PHARMACEUTICAL IND. CO., LTD. | 2010-09-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100240890-A1 | Novel benzamidine derivatives, process for the preparation thereof and pharmaceutical composition comprising the same | CMA1, IL5, HRH4 | ALDH1A1 1751/4885TDP1 3507/4885L3MBTL1 3894/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.