Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 5/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | IDO1 | P14902 | 2/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | ATAD2 | Q6PL18 | 1/20 | 0.39 |
| ▸ | CECR2 | Q9BXF3 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1819956 | 0.84 | ALDH1A1 (0.45) | RORCALDH1A1IDO1SMN1; SMN2LMNA | |
| SCHEMBL1816036 | 0.83 | IDO1 (0.39) | RORCALDH1A1IDO1LMNAL3MBTL1 | |
| SCHEMBL1817314 | 0.82 | HPGD (0.40) | RORCALDH1A1LMNAL3MBTL1POLB | |
| SCHEMBL1818124 | 0.81 | GAA (0.50) | RORCALDH1A1SMN1; SMN2LMNAL3MBTL1 | |
| SCHEMBL31311192 | 0.79 | KMT2A (0.38) | RORCALDH1A1IDO1POLB | |
| SCHEMBL1008664 | 0.78 | RORC (0.52) | RORCALDH1A1SMN1; SMN2PTK2LMNA | |
| SCHEMBL31311285 | 0.77 | RORC (0.44) | RORCALDH1A1SMN1; SMN2LMNATP53 | |
| SCHEMBL28134648 | 0.77 | RORC (0.51) | RORCALDH1A1SMN1; SMN2PTK2LMNA | |
| SCHEMBL21598720 | 0.75 | MALT1 (0.44) | RORCALDH1A1IDO1ATMATAD2 | |
| SCHEMBL1675548 | 0.72 | RORC (0.47) | RORCALDH1A1IDO1SMN1; SMN2PTK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110212918-A1 | BORON-CONTAINING SMALL MOLECULES | ANACOR PHARMACEUTICALS, INC. (US) | 2011-09-01 | — | — | US | disclosed |
| WO-2011060199-A1 | BORON-CONTAINING SMALL MOLECULES | ANACOR PHARMACEUTICALS, INC. (US) | 2011-05-19 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110212918-A1 | BORON-CONTAINING SMALL MOLECULES | BCL6B, BCL6, BTD | RORC 1616/4885ALDH1A1 4190/4885IDO1 3398/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.