Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | MITF | O75030 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.41 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.41 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.41 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | TSPO | P30536 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13151277 | 0.84 | NPY5R (0.41) | ALDH1A1LMNAMEN1TSHRKMT2A | |
| SCHEMBL18175980 | 0.84 | PBRM1 (0.49) | KDM4EALDH1A1PBRM1NPC1MITF | |
| SCHEMBL12677920 | 0.83 | HPGD (0.59) | HPGDTDP1 | |
| SCHEMBL24568139 | 0.80 | NPY5R (0.50) | ALDH1A1HPGDTSPO | |
| SCHEMBL12852628 | 0.79 | NPY5R (0.42) | ALDH1A1LMNATSHRKMT2A | |
| SCHEMBL13034568 | 0.78 | GSK3B (0.49) | KDM4EALDH1A1POLBMEN1TSHR | |
| SCHEMBL20888440 | 0.78 | NPY5R (0.41) | ALDH1A1LMNAHPGDTSPOTSHR | |
| SCHEMBL1172823 | 0.77 | PBRM1 (0.55) | KDM4EALDH1A1PBRM1NPC1MITF | |
| SCHEMBL27572329 | 0.77 | PBRM1 (0.41) | KDM4EALDH1A1PBRM1NPC1MITF | |
| SCHEMBL13369998 | 0.76 | PBRM1 (0.50) | KDM4EALDH1A1PBRM1NPC1MITF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2417120-B1 | SUBSTITUTED PIPERIDINES AS CCR3 ANTAGONISTS | BOEHRINGER INGELHEIM INT (DE) | 2016-10-26 | — | — | EP | disclosed |