Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | MITF | O75030 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.42 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.42 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.42 |
| ▸ | F2 | P00734 | 1/20 | 0.42 |
| ▸ | PLG | P00747 | 1/20 | 0.42 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.42 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.42 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 2/20 | 0.41 |
| ▸ | CA2 | P00918 | 2/20 | 0.41 |
| ▸ | CA9 | Q16790 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13369998 | 0.84 | PBRM1 (0.50) | PBRM1NPC1MITFLMNAPOLB | |
| SCHEMBL18175925 | 0.84 | KDM4E (0.44) | PBRM1NPC1MITFLMNAPOLB | |
| SCHEMBL1172823 | 0.82 | PBRM1 (0.55) | PBRM1NPC1MITFLMNAPOLB | |
| SCHEMBL27572329 | 0.82 | PBRM1 (0.41) | PBRM1NPC1MITFLMNAPOLB | |
| SCHEMBL22318570 | 0.81 | CA12 (0.50) | POLBALDH1A1KDM4ECA1CA2 | |
| Hydrochloric Acid SCHEMBL27784476 | 0.80 | PBRM1 (0.53) | PBRM1NPC1MITFLMNAPOLB | |
| SCHEMBL24766663 | 0.80 | PBRM1 (0.46) | PBRM1NPC1MITFLMNAPOLB | |
| SCHEMBL19592399 | 0.79 | F2 (0.42) | PBRM1NPC1MITFLMNAPOLB | |
| SCHEMBL13412201 | 0.79 | CES2 (0.53) | NPC1ALDH1A1ADRB2ADRB1ADRB3 | |
| SCHEMBL1196746 | 0.79 | KMT2A (0.39) | MEN1KMT2AHSD17B10GAAADORA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2417120-B1 | SUBSTITUTED PIPERIDINES AS CCR3 ANTAGONISTS | BOEHRINGER INGELHEIM INT (DE) | 2016-10-26 | — | — | EP | disclosed |