SCHEMBL18175957

SCHEMBL18175957

O=C1OC(Cc2ccccc2)C(C(=O)O)O1

nearest known ligand 0.42

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
CTRB1 P17538 1/20 0.42
TLR9 Q9NR96 1/20 0.41
FASN P49327 1/20 0.41
GRM2 Q14416 1/20 0.36
F2 P00734 2/20 0.36
PRSS1 P07477 2/20 0.36
CES2 O00748 1/20 0.35
CES1 P23141 1/20 0.35
AKR1B1 P15121 1/20 0.35
ABCB1 P08183 1/20 0.34
EP300 Q09472 1/20 0.33
KDM4E B2RXH2 1/20 0.33
LMNA P02545 1/20 0.33
MAPT P10636 1/20 0.33
HIF1A Q16665 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11000844 0.83 CTRB1 (0.52) CTRB1TLR9FASNGRM2F2
SCHEMBL20253618 0.83 BACE1 (0.45) CTRB1TLR9FASNKDM4EMAPT
SCHEMBL5194706 0.78 TLR9 (0.46) CTRB1TLR9FASNCES2CES1
SCHEMBL5194710 0.78 TLR9 (0.46) CTRB1TLR9FASNCES2CES1
SCHEMBL5194716 0.78 TLR9 (0.46) CTRB1TLR9FASNCES2CES1
SCHEMBL3684121 0.78 TLR9 (0.46) CTRB1TLR9FASNCES2CES1
SCHEMBL20253606 0.77 NPC1 (0.40) CTRB1TLR9FASN
SCHEMBL16438910 0.75 CTRB1 (0.45) CTRB1TLR9FASNGRM2F2
SCHEMBL25629020 0.74 CTRB1 (0.56) CTRB1FASNGRM2F2PRSS1
SCHEMBL25629015 0.74 CTRB1 (0.56) CTRB1FASNGRM2F2PRSS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3086396-A1 NONAQUEOUS ELECTROLYTE, CAPACITOR DEVICE USING SAME, AND CARBOXYLIC ACID ESTER COMPOUND USED IN SAME UBE Industries, Ltd. (JP) 2016-10-26 EP disclosed