Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.50 |
| ▸ | RRM1 | P23921 | 1/20 | 0.49 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.42 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.42 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.42 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 2/20 | 0.39 |
| ▸ | CA2 | P00918 | 2/20 | 0.39 |
| ▸ | DNM1 | Q05193 | 5/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.39 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.38 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28548753 | 0.98 | RRM1 (0.51) | DPP7RRM1GNAI3GNAO1GNAI1 | |
| SCHEMBL27533018 | 0.98 | RRM1 (0.51) | DPP7RRM1GNAI3GNAO1GNAI1 | |
| SCHEMBL29002310 | 0.98 | RRM1 (0.51) | DPP7RRM1GNAI3GNAO1GNAI1 | |
| SCHEMBL29002293 | 0.98 | RRM1 (0.51) | DPP7RRM1GNAI3GNAO1GNAI1 | |
| SCHEMBL2377049 | 0.93 | DPP7 (0.43) | DPP7RRM1GNAI3GNAO1GNAI1 | |
| SCHEMBL22806603 | 0.88 | GNAI3 (0.51) | DPP7RRM1GNAI3GNAO1GNAI1 | |
| SCHEMBL13707476 | 0.86 | — | — | |
| SCHEMBL8389662 | 0.86 | CA12 (0.40) | DPP7RRM1GNAI3GNAO1GNAI1 | |
| SCHEMBL22806604 | 0.86 | GNAI3 (0.54) | DPP7RRM1GNAI3GNAO1GNAI1 | |
| SCHEMBL22806602 | 0.85 | SPHK1 (0.45) | DPP7RRM1GNAI3GNAO1GNAI1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3085388-A1 | HYPERBRANCHED POLYMER CONJUGATES VIA NON-ENZYMATIC CLEAVABLE LINKER | Ascendis Pharma Growth Disorders Division A/S (DK) | 2016-10-26 | — | — | EP | disclosed |