Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | LTB4R | Q15722 | 2/20 | 0.34 |
| ▸ | LTB4R2 | Q9NPC1 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | METAP1 | P53582 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | ACACB | O00763 | 1/20 | 0.32 |
| ▸ | ACACA | Q13085 | 1/20 | 0.32 |
| ▸ | METAP2 | P50579 | 1/20 | 0.32 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.31 |
| ▸ | PTGFR | P43088 | 1/20 | 0.31 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.31 |
| ▸ | NMT2 | O60551 | 1/20 | 0.30 |
| ▸ | NMT1 | P30419 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL111408 | 0.80 | CYP1A2 (0.48) | CYP1A2METAP1MAPTSIGMAR1TSHR | |
| SCHEMBL30754374 | 0.80 | CYP1A2 (0.48) | CYP1A2METAP1MAPTSIGMAR1TSHR | |
| SCHEMBL29102100 | 0.80 | METAP1 (0.44) | CYP1A2METAP1SIGMAR1TSHRMETAP2 | |
| SCHEMBL28126617 | 0.79 | METAP1 (0.41) | ALDH1A1KMT2ALTB4RLTB4R2CYP1A2 | |
| SCHEMBL28058901 | 0.77 | CYP1A2 (0.50) | ALDH1A1KMT2ACYP1A2TBXA2RPTGFR | |
| SCHEMBL14228626 | 0.77 | FFAR4 (0.46) | ALDH1A1KMT2ACYP1A2TBXA2RPTGFR | |
| Alcohol SCHEMBL17544758 | 0.77 | CYP1A2 (0.50) | CYP1A2METAP1MAPTSIGMAR1TSHR | |
| SCHEMBL11739573 | 0.76 | METAP1 (0.42) | ALDH1A1CYP1A2METAP1MAPTSIGMAR1 | |
| SCHEMBL7429602 | 0.75 | METAP1 (0.50) | CYP1A2METAP1SIGMAR1METAP2 | |
| SCHEMBL8585482 | 0.75 | SIGMAR1 (0.48) | ALDH1A1KMT2ACYP1A2METAP1SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3085388-A1 | HYPERBRANCHED POLYMER CONJUGATES VIA NON-ENZYMATIC CLEAVABLE LINKER | Ascendis Pharma Growth Disorders Division A/S (DK) | 2016-10-26 | — | — | EP | disclosed |