Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 8/20 | 0.71 |
| ▸ | RAB9A | P51151 | 7/20 | 0.71 |
| ▸ | EPHX2 | P34913 | 5/20 | 0.71 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.71 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.57 |
| ▸ | DRD2 | P14416 | 1/20 | 0.57 |
| ▸ | DRD4 | P21917 | 1/20 | 0.57 |
| ▸ | DRD3 | P35462 | 1/20 | 0.57 |
| ▸ | FAAH | O00519 | 1/20 | 0.57 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | CTSL | P07711 | 1/20 | 0.52 |
| ▸ | CTSB | P07858 | 1/20 | 0.52 |
| ▸ | CTSS | P25774 | 1/20 | 0.52 |
| ▸ | CTSC | P53634 | 1/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | CDK9 | P50750 | 1/20 | 0.52 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15263046 | 0.91 | EPHX1 (0.83) | EPHX1RAB9AEPHX2SMN1; SMN2ALDH1A1 | |
| SCHEMBL10825858 | 0.91 | EPHX1 (0.83) | EPHX1RAB9AEPHX2SMN1; SMN2ALDH1A1 | |
| SCHEMBL584079 | 0.87 | EPHX1 (0.71) | EPHX1RAB9AEPHX2SMN1; SMN2ALDH1A1 | |
| SCHEMBL584080 | 0.87 | EPHX1 (0.71) | EPHX1RAB9AEPHX2SMN1; SMN2ALDH1A1 | |
| SCHEMBL5469266 | 0.86 | EPHX1 (0.75) | EPHX1RAB9AEPHX2SMN1; SMN2ALDH1A1 | |
| SCHEMBL5469269 | 0.86 | EPHX1 (0.75) | EPHX1RAB9AEPHX2SMN1; SMN2ALDH1A1 | |
| SCHEMBL13949482 | 0.85 | EPHX1 (0.73) | EPHX1RAB9AEPHX2SMN1; SMN2ALDH1A1 | |
| SCHEMBL4266974 | 0.85 | EPHX1 (0.73) | EPHX1RAB9AEPHX2SMN1; SMN2ALDH1A1 | |
| SCHEMBL2752734 | 0.84 | RAB9A (0.96) | EPHX1RAB9AEPHX2SMN1; SMN2ALDH1A1 | |
| SCHEMBL28218814 | 0.84 | EPHX1 (0.90) | EPHX1RAB9AEPHX2SMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2417120-B1 | SUBSTITUTED PIPERIDINES AS CCR3 ANTAGONISTS | BOEHRINGER INGELHEIM INT (DE) | 2016-10-26 | — | — | EP | disclosed |