Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.40 |
| ▸ | TSHR | P16473 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 3/20 | 0.35 |
| ▸ | EGFR | P00533 | 1/20 | 0.34 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.34 |
| ▸ | CNR2 | P34972 | 3/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | GLA | P06280 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.31 |
| ▸ | ALDH1A3 | P47895 | 1/20 | 0.31 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.31 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.31 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1812804 | 0.90 | ALDH1A1 (0.42) | ALDH1A1CYP3A4TSHRLMNAHSD17B10 | |
| SCHEMBL8438809 | 0.82 | ALDH1A1 (0.46) | ALDH1A1CYP3A4TSHRLMNAHSD17B10 | |
| SCHEMBL8440732 | 0.82 | ALDH1A1 (0.46) | ALDH1A1CYP3A4TSHRLMNAHSD17B10 | |
| SCHEMBL22620082 | 0.81 | ALDH1A1 (0.43) | ALDH1A1CYP3A4TSHRLMNAHSD17B10 | |
| SCHEMBL11329199 | 0.81 | ALDH1A1 (0.41) | ALDH1A1CYP3A4TSHRLMNAHSD17B10 | |
| SCHEMBL7766631 | 0.80 | ALDH1A1 (0.48) | ALDH1A1CYP3A4TSHRLMNAHSD17B10 | |
| Hydrochloric Acid SCHEMBL11407281 | 0.80 | ALDH1A1 (0.40) | ALDH1A1CYP3A4TSHRLMNAHSD17B10 | |
| SCHEMBL5471860 | 0.80 | ALDH1A1 (0.40) | ALDH1A1CYP3A4TSHRLMNAHSD17B10 | |
| SCHEMBL11904607 | 0.80 | ALDH1A1 (0.43) | ALDH1A1CYP3A4TSHRLMNAKDM4E | |
| SCHEMBL411184 | 0.79 | ALDH1A1 (0.49) | ALDH1A1CYP3A4TSHRLMNAHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8703682-B2 | Lubrication and lubricating oil compositions | INFINEUM INTERNATIONAL LIMITED (GB) | 2014-04-22 | — | — | US | claimed |
| EP-2319904-B1 | Lubrication and lubricating oil compositions comprising phenylene diamines | INFINEUM INT LTD (GB) | 2012-07-11 | — | — | EP | claimed |
| EP-2319904-A1 | Lubrication and lubricating oil compositions comprising phenylene diamines | Infineum International Limited (GB) | 2011-05-11 | — | — | EP | claimed |
| US-20110105372-A1 | Lubrication and Lubricating Oil Compositions | LANXESS SOLUTIONS US INC. | 2011-05-05 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110105372-A1 | Lubrication and Lubricating Oil Compositions | TAF9, FLNA, FLNB | ALDH1A1 956/4885CYP3A4 1721/4885TSHR 1806/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.