Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.59 |
| ▸ | EGFR | P00533 | 3/20 | 0.59 |
| ▸ | LMNA | P02545 | 2/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.59 |
| ▸ | HTT | P42858 | 2/20 | 0.59 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.59 |
| ▸ | GALR2 | O43603 | 1/20 | 0.59 |
| ▸ | SYK | P43405 | 1/20 | 0.59 |
| ▸ | VCP | P55072 | 1/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.59 |
| ▸ | HPGD | P15428 | 2/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.54 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.54 |
| ▸ | ALDH5A1 | P51649 | 1/20 | 0.54 |
| ▸ | ABAT | P80404 | 1/20 | 0.54 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1971749 | 0.88 | VCP (0.55) | MAPTALDH1A1EGFRLMNAMAPK1 | |
| SCHEMBL1971750 | 0.88 | VCP (0.55) | MAPTALDH1A1EGFRLMNAMAPK1 | |
| SCHEMBL16929832 | 0.86 | VCP (0.45) | MAPTALDH1A1EGFRLMNAMAPK1 | |
| SCHEMBL16929830 | 0.86 | VCP (0.45) | MAPTALDH1A1EGFRLMNAMAPK1 | |
| SCHEMBL16929943 | 0.81 | KDM4E (0.50) | MAPTALDH1A1LMNAMAPK1HTT | |
| SCHEMBL16929944 | 0.81 | KDM4E (0.50) | MAPTALDH1A1LMNAMAPK1HTT | |
| SCHEMBL16929908 | 0.80 | VCP (0.41) | MAPTALDH1A1EGFRLMNAMAPK1 | |
| SCHEMBL16929907 | 0.80 | VCP (0.41) | MAPTALDH1A1EGFRLMNAMAPK1 | |
| SCHEMBL16930169 | 0.80 | VCP (0.43) | MAPTALDH1A1EGFRLMNAMAPK1 | |
| SCHEMBL16930167 | 0.80 | VCP (0.43) | MAPTALDH1A1EGFRLMNAMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160310528-A1 | Castration-Resistant Prostate Cancer | NUTECH VENTURES | 2016-10-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160310528-A1 | Castration-Resistant Prostate Cancer | UGDH, G6PD, DPYD | MAPT 2722/4885ALDH1A1 54/4885EGFR 4259/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.