Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSD | P07339 | 1/20 | 0.54 |
| ▸ | PAOX | Q6QHF9 | 4/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | KDM5C | P41229 | 1/20 | 0.48 |
| ▸ | PHF8 | Q9UPP1 | 1/20 | 0.48 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.48 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.38 |
| ▸ | PARP1 | P09874 | 1/20 | 0.38 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27466487 | 0.98 | PAOX (0.56) | CTSDPAOXALDH1A1GAAKDM4E | |
| SCHEMBL27351689 | 0.95 | CTSD (0.54) | CTSDPAOXALDH1A1GAAKDM4E | |
| SCHEMBL7077808 | 0.91 | PAOX (0.50) | CTSDPAOXALDH1A1GAAKDM4E | |
| Acetone SCHEMBL6392906 | 0.90 | CTSD (0.59) | CTSDPAOXALDH1A1GAAKDM4E | |
| Acetone SCHEMBL22554792 | 0.90 | CTSD (0.59) | CTSDPAOXALDH1A1GAAKDM4E | |
| Acetic Acid SCHEMBL6534753 | 0.87 | CTSD (0.56) | CTSDPAOXALDH1A1GAAKDM4E | |
| SCHEMBL5606148 | 0.87 | CTSD (0.56) | CTSDPAOXALDH1A1GAAKDM4E | |
| SCHEMBL28219205 | 0.87 | ALDH1A1 (0.62) | CTSDALDH1A1GAAKDM4EKDM5C | |
| SCHEMBL49856 | 0.87 | ALDH1A1 (0.62) | CTSDALDH1A1GAAKDM4EKDM5C | |
| SCHEMBL16359624 | 0.84 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160311970-A1 | INSERTION POLYNORBORNENE-BASED THERMOSET RESINS | CLAVERIE, Jérôme (CA) | 2016-10-27 | — | — | US | disclosed |