Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.66 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.66 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.66 |
| ▸ | HTT | P42858 | 1/20 | 0.66 |
| ▸ | ABCC1 | P33527 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.56 |
| ▸ | BCHE | P06276 | 1/20 | 0.55 |
| ▸ | ACHE | P22303 | 1/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.55 |
| ▸ | KCNJ1 | P48048 | 1/20 | 0.55 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | TP53 | P04637 | 1/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3161300 | 0.85 | ALDH1A1 (0.61) | KDM4EALDH1A1SMN1; SMN2HTTABCC1 | |
| SCHEMBL1600111 | 0.84 | KMT2A (0.65) | KDM4EALDH1A1KMT2AMAPK1MEN1 | |
| SCHEMBL18177860 | 0.84 | KDM4E (0.63) | KDM4EALDH1A1SMN1; SMN2HTTABCC1 | |
| SCHEMBL18177850 | 0.82 | KCNJ1 (0.61) | KDM4EALDH1A1SMN1; SMN2HTTABCC1 | |
| SCHEMBL6131992 | 0.80 | KMT2A (0.60) | KDM4EALDH1A1SMN1; SMN2HTTKMT2A | |
| SCHEMBL11556531 | 0.80 | MAPK1 (0.69) | ALDH1A1SMN1; SMN2ABCC1KMT2AMAPK1 | |
| SCHEMBL3156573 | 0.80 | ABCB1 (0.69) | KDM4EALDH1A1SMN1; SMN2HTTABCC1 | |
| SCHEMBL22304876 | 0.79 | ALDH1A1 (0.62) | KDM4EALDH1A1SMN1; SMN2HTTKMT2A | |
| Methane SCHEMBL20459317 | 0.79 | KDM4E (0.60) | KDM4EALDH1A1SMN1; SMN2HTTMAPK1 | |
| SCHEMBL374154 | 0.78 | KDM4E (0.67) | KDM4EALDH1A1SMN1; SMN2KMT2AMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200071735-A1 | Compounds for Increasing Lipid Synthesis and Storage | WASE, NISHIKANT | 2020-03-05 | — | — | US | disclosed |
| US-10351883-B2 | Compounds for increasing lipid synthesis and storage | NUTECH VENTURES (US) | 2019-07-16 | — | — | US | disclosed |
| US-20160312253-A1 | Compounds for Increasing Lipid Synthesis and Storage | INVITROGEN CORPORATION | 2016-10-27 | — | — | US | disclosed |
| US-20160312253-A1 | Compounds for Increasing Lipid Synthesis and Storage | INVITROGEN CORPORATION | 2016-10-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160312253-A1 | Compounds for Increasing Lipid Synthesis and Storage | FASN, LIPC, SREBF2 | KDM4E 1755/4885ALDH1A1 1121/4885SMN1; SMN2 4517/4885 |
| US-10351883-B2 | Compounds for increasing lipid synthesis and storage | FASN, LIPC, SREBF2 | KDM4E 1755/4885ALDH1A1 1121/4885SMN1; SMN2 4517/4885 |
| US-20200071735-A1 | Compounds for Increasing Lipid Synthesis and Storage | FASN, LIPC, SREBF2 | KDM4E 1755/4885ALDH1A1 1121/4885SMN1; SMN2 4517/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.