Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 10/20 | 0.43 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.41 |
| ▸ | HTR1A | P08908 | 1/20 | 0.41 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.41 |
| ▸ | DRD1 | P21728 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.41 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.41 |
| ▸ | DRD3 | P35462 | 1/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.41 |
| ▸ | KDM5A | P29375 | 1/20 | 0.39 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.38 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.36 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.36 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18158071 | 0.97 | KCNH2 (0.42) | KCNH2CHRM2HTR1AADRA2ACHRM1 | |
| SCHEMBL20927416 | 0.94 | KCNH2 (0.45) | KCNH2SIGMAR1DNM1PLA2G1BPLA2G2A | |
| SCHEMBL2874914 | 0.94 | KCNH2 (0.50) | KCNH2KDM5AKDM4CDNM1PLA2G1B | |
| SCHEMBL8288008 | 0.91 | KCNH2 (0.53) | KCNH2DNM1PLA2G1BPLA2G2A | |
| SCHEMBL10879676 | 0.91 | KCNH2 (0.53) | KCNH2DNM1PLA2G1BPLA2G2A | |
| SCHEMBL20299290 | 0.91 | KCNH2 (0.53) | KCNH2DNM1PLA2G1BPLA2G2A | |
| SCHEMBL19068004 | 0.91 | KCNH2 (0.44) | KCNH2SIGMAR1DNM1 | |
| Hydrochloric Acid SCHEMBL22771831 | 0.91 | KCNH2 (0.48) | KCNH2KDM5AKDM4CDNM1PLA2G1B | |
| SCHEMBL10821020 | 0.91 | KCNH2 (0.53) | KCNH2DNM1PLA2G1BPLA2G2A | |
| SCHEMBL14287243 | 0.91 | KCNH2 (0.53) | KCNH2DNM1PLA2G1BPLA2G2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11498853-B2 | Water with switchable ionic strength | QUEEN'S UNIVERSITY AT KINGSTON | 2022-11-15 | — | — | US | claimed |
| EP-2493849-B1 | METHOD OF SEPARATION EMPLOYING SWITCHABLE HYDROPHILICITY SOLVENTS | UNIV KINGSTON (CA) | 2021-12-08 | — | — | EP | claimed |
| EP-2534106-B1 | METHOD FOR MODULATING IONIC STRENGTH | UNIV KINGSTON (CA) | 2019-10-16 | — | — | EP | claimed |
| US-20150240051-A1 | SWITCHABLE HYDROPHILICITY SOLVENTS AND METHODS OF USE THEREOF | GREENCENTRE CANADA (CA) | 2015-08-27 | — | — | US | claimed |
| US-8580124-B2 | Switchable hydrophilicity solvents and methods of use thereof | QUEEN'S UNIVERSITY AT KINGSTON (CA) | 2013-11-12 | — | — | US | claimed |
| EP-2651992-A1 | SYSTEMS AND METHODS FOR USE OF WATER WITH SWITCHABLE IONIC STRENGTH | Queen's University At Kingston (CA) | 2013-10-23 | — | — | EP | claimed |
| US-20130105377-A1 | Water with Switchable Ionic Strength | QUEEN'S UNIVERSITY AT KINGSTON (CA) | 2013-05-02 | — | — | US | claimed |
| EP-2534106-A1 | WATER WITH SWITCHABLE IONIC STRENGTH | Queen's University At Kingston (CA) | 2012-12-19 | — | — | EP | claimed |
| EP-2493849-A1 | SWITCHABLE HYDROPHILICITY SOLVENTS AND METHODS OF USE THEREOF | Queen's University At Kingston (CA) | 2012-09-05 | — | — | EP | claimed |
| WO-2012079175-A1 | SYSTEMS AND METHODS FOR USE OF WATER WITH SWITCHABLE IONIC STRENGTH | QUEEN'S UNIVERSITY AT KINGSTON (CA) | 2012-06-21 | — | — | WO | claimed |
| US-20110257334-A1 | Switchable Hydrophilicity Solvents and Methods of Use Thereof | QUEEN'S UNIVERSITY AT KINGSTON (CA) | 2011-10-20 | — | — | US | claimed |
| WO-2011097727-A1 | WATER WITH SWITCHABLE IONIC STRENGTH | QUEEN'S UNIVERSITY AT KINGSTON (CA) | 2011-08-18 | — | — | WO | claimed |
| WO-2011050469-A1 | SWITCHABLE HYDROPHILICITY SOLVENTS AND METHODS OF USE THEREOF | QUEEN'S UNIVERSITY AT KINGSTON (CA) | 2011-05-05 | — | — | WO | claimed |
| EP-3653584-B1 | DRAW SOLUTION WITH SWITCHABLE SALT ADDITIVE AND METHOD FOR DESALINATING AN AQUEOUS SOLUTION WITH THIS DRAW SOLUTION | UNIV KINGSTON (CA) | 2025-08-06 | — | — | EP | disclosed |
| US-11498853-B2 | Water with switchable ionic strength | QUEEN'S UNIVERSITY AT KINGSTON | 2022-11-15 | — | — | US | disclosed |
| EP-2493849-B1 | METHOD OF SEPARATION EMPLOYING SWITCHABLE HYDROPHILICITY SOLVENTS | UNIV KINGSTON (CA) | 2021-12-08 | — | — | EP | disclosed |
| WO-2012079175-A1 | SYSTEMS AND METHODS FOR USE OF WATER WITH SWITCHABLE IONIC STRENGTH | QUEEN'S UNIVERSITY AT KINGSTON (CA) | 2012-06-21 | — | — | WO | disclosed |
| US-20110257334-A1 | Switchable Hydrophilicity Solvents and Methods of Use Thereof | QUEEN'S UNIVERSITY AT KINGSTON (CA) | 2011-10-20 | — | — | US | disclosed |
| WO-2011097727-A1 | WATER WITH SWITCHABLE IONIC STRENGTH | QUEEN'S UNIVERSITY AT KINGSTON (CA) | 2011-08-18 | — | — | WO | disclosed |
| WO-2011050469-A1 | SWITCHABLE HYDROPHILICITY SOLVENTS AND METHODS OF USE THEREOF | QUEEN'S UNIVERSITY AT KINGSTON (CA) | 2011-05-05 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110257334-A1 | Switchable Hydrophilicity Solvents and Methods of Use Thereof | AQP4, AQP1, AQP3 | KCNH2 1700/4885CHRM2 265/4885HTR1A 4101/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.