Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MRGPRX4 | Q96LA9 | 4/20 | 0.50 |
| ▸ | MRGPRX1 | Q96LB2 | 3/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.38 |
| ▸ | FFAR1 | O14842 | 5/20 | 0.37 |
| ▸ | PPARD | Q03181 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.37 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.36 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | STING1 | Q86WV6 | 1/20 | 0.36 |
| ▸ | HRH1 | P35367 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18178443 | 0.91 | MRGPRX4 (0.52) | MRGPRX4FFAR1 | |
| SCHEMBL18178052 | 0.90 | MRGPRX4 (0.49) | MRGPRX4MRGPRX1PTGS1PTGS2FFAR1 | |
| SCHEMBL18178444 | 0.89 | MRGPRX4 (0.51) | MRGPRX4FFAR1MAPTL3MBTL1RAB9A | |
| SCHEMBL18178445 | 0.88 | MRGPRX4 (0.50) | MRGPRX4FFAR1MAPTL3MBTL1HPGD | |
| SCHEMBL18178484 | 0.88 | MRGPRX4 (0.48) | MRGPRX4FFAR1MAPTKCNMA1L3MBTL1 | |
| SCHEMBL18182418 | 0.87 | LMNA (0.41) | MRGPRX4PTGS1PTGS2FFAR1PPARD | |
| SCHEMBL18178440 | 0.87 | MRGPRX4 (0.49) | MRGPRX4FFAR1MAPTRAB9A | |
| SCHEMBL18178447 | 0.87 | MRGPRX4 (0.49) | MRGPRX4FFAR1MAPTL3MBTL1RAB9A | |
| SCHEMBL18178442 | 0.87 | MRGPRX4 (0.49) | MRGPRX4MRGPRX1PTGS2FFAR1 | |
| SCHEMBL18178508 | 0.87 | MRGPRX4 (0.37) | MRGPRX4MRGPRX1PTGS1PTGS2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9573904-B2 | Aromatic compound and use thereof | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2017-02-21 | — | — | US | disclosed |
| US-20160311775-A1 | AROMATIC COMPOUND AND USE THEREOF | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2016-10-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160311775-A1 | AROMATIC COMPOUND AND USE THEREOF | ZCCHC8, CBR3, CBX8 | MRGPRX4 167/4885MRGPRX1 359/4885PTGS1 4413/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.