Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.49 |
| ▸ | MRGPRX1 | Q96LB2 | 3/20 | 0.40 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.38 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.38 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | KCNK3 | O14649 | 2/20 | 0.37 |
| ▸ | KCNK9 | Q9NPC2 | 2/20 | 0.37 |
| ▸ | HRH1 | P35367 | 1/20 | 0.37 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.37 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | KCNB1 | Q14721 | 1/20 | 0.37 |
| ▸ | TNFRSF1A | P19438 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | PPARD | Q03181 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18178446 | 0.90 | MRGPRX4 (0.50) | MRGPRX4MRGPRX1KCNMA1KCNQ3KCNQ2 | |
| SCHEMBL18178045 | 0.90 | MRGPRX4 (0.52) | MRGPRX4FFAR1ALDH1A1MEN1LMNA | |
| SCHEMBL18178117 | 0.89 | MRGPRX4 (0.49) | MRGPRX4SMN1; SMN2FFAR1ALDH1A1POLB | |
| SCHEMBL18178071 | 0.88 | MRGPRX4 (0.47) | MRGPRX4KCNMA1SMN1; SMN2KCNK3KCNK9 | |
| SCHEMBL18178043 | 0.88 | MRGPRX4 (0.51) | MRGPRX4SMN1; SMN2FFAR1ALDH1A1LMNA | |
| SCHEMBL18182453 | 0.88 | LMNA (0.42) | MRGPRX4KCNQ3KCNQ2PTGS1PTGS2 | |
| SCHEMBL18178082 | 0.88 | KCNMA1 (0.38) | MRGPRX4MRGPRX1KCNMA1SMN1; SMN2KCNK3 | |
| SCHEMBL18178109 | 0.87 | L3MBTL1 (0.41) | MRGPRX4KCNMA1KCNK3KCNK9KCNA5 | |
| SCHEMBL18178350 | 0.87 | PTGS1 (0.38) | MRGPRX4PTGS1PTGS2KCNK3KCNK9 | |
| SCHEMBL18178114 | 0.86 | MRGPRX4 (0.49) | MRGPRX4SMN1; SMN2FFAR1ALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9573904-B2 | Aromatic compound and use thereof | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2017-02-21 | — | — | US | disclosed |
| US-20160311775-A1 | AROMATIC COMPOUND AND USE THEREOF | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2016-10-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160311775-A1 | AROMATIC COMPOUND AND USE THEREOF | ZCCHC8, CBR3, CBX8 | MRGPRX4 167/4885MRGPRX1 359/4885KCNMA1 1196/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.