Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | SGMS2 | Q8NHU3 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | PPARD | Q03181 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | GUCY1B2 | O75343 | 1/20 | 0.35 |
| ▸ | GUCY1A2 | P33402 | 1/20 | 0.35 |
| ▸ | GUCY1A1 | Q02108 | 1/20 | 0.35 |
| ▸ | GUCY1B1 | Q02153 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | ACLY | P53396 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18178703 | 0.92 | ALDH1A1 (0.36) | ALDH1A1KMT2AATML3MBTL1POLB | |
| SCHEMBL18178658 | 0.92 | SLC22A12 (0.37) | ALDH1A1MAPTSGMS2RAB9AGAA | |
| SCHEMBL18178773 | 0.91 | GUCY1B2 (0.37) | PPARDGUCY1B2GUCY1A2GUCY1A1GUCY1B1 | |
| SCHEMBL18178677 | 0.91 | MRGPRX4 (0.36) | ALDH1A1KMT2AATML3MBTL1POLB | |
| SCHEMBL18178596 | 0.90 | MRGPRX4 (0.37) | PPARDGUCY1B2GUCY1A2GUCY1A1GUCY1B1 | |
| SCHEMBL18178297 | 0.90 | SGMS2 (0.39) | ALDH1A1KMT2AATML3MBTL1POLB | |
| SCHEMBL18178674 | 0.90 | MRGPRX4 (0.39) | ALDH1A1KMT2AL3MBTL1MAPTGAA | |
| SCHEMBL18182447 | 0.90 | ALDH1A1 (0.39) | ALDH1A1KMT2AATML3MBTL1POLB | |
| SCHEMBL18178639 | 0.89 | ALDH1A1 (0.39) | ALDH1A1KMT2AATML3MBTL1POLB | |
| SCHEMBL18178653 | 0.89 | ALDH1A1 (0.39) | ALDH1A1KMT2AATML3MBTL1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9573904-B2 | Aromatic compound and use thereof | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2017-02-21 | — | — | US | disclosed |
| US-20160311775-A1 | AROMATIC COMPOUND AND USE THEREOF | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2016-10-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160311775-A1 | AROMATIC COMPOUND AND USE THEREOF | ZCCHC8, CBR3, CBX8 | ALDH1A1 3176/4885KMT2A 2232/4885ATM 1683/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.