Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18180932 | 0.80 | MEN1 (0.31) | ALDH1A1MEN1MAPTKMT2A | |
| SCHEMBL30174115 | 0.77 | MAPK1 (0.42) | — | |
| SCHEMBL10307511 | 0.77 | MAPK1 (0.42) | — | |
| SCHEMBL18180872 | 0.65 | MAPK1 (0.30) | — | |
| SCHEMBL18180877 | 0.65 | MEN1 (0.30) | ALDH1A1MEN1MAPTKMT2A | |
| SCHEMBL18180874 | 0.64 | — | — | |
| SCHEMBL18180882 | 0.63 | FNTA (0.45) | ALDH1A1MEN1MAPTKMT2A | |
| Grossheimin SCHEMBL1711493 | 0.63 | MAPT (0.34) | ALDH1A1MEN1MAPTKMT2A | |
| Grossheimin SCHEMBL1711489 | 0.63 | MAPT (0.34) | ALDH1A1MEN1MAPTKMT2A | |
| SCHEMBL18180870 | 0.63 | NFE2L2 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016169573-A1 | SESQUITERPENE LACTONES AS POTENT AND BROAD SPECTRUM ANTIVIRAL COMPOUNDS AGAINST ALL GENOTYPES OF HEPATITIS C VIRUS (HCV) | ELSEBAI MAHMOUD FAHMI (EG) | 2016-10-27 | — | — | WO | disclosed |