SCHEMBL18180917

C=C1C[C@H](O[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)[C@@H]2[C@H](OC(=O)[C@H]2C)[C@H]2[C@H](C)[C@H](O)C[C@@H]12

nearest known ligand 0.48

Predicted protein targets (top 6)

	gene	UniProt	supporting neighbours	confidence
▸	MAPT	P10636	2/20	0.48

▸	STAT3	P40763	14/20	0.47

▸	PTPN1	P18031	2/20	0.42

▸	MEN1	O00255	1/20	0.39

▸	KMT2A	Q03164	1/20	0.39

▸	SYNJ2	O15056	1/20	0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL31097625	0.87	PTPN1 (0.44)	MAPTSTAT3PTPN1MEN1KMT2A
SCHEMBL30440792	0.69	STAT3 (0.40)	MAPTSTAT3PTPN1MEN1KMT2A
Loganic Acid SCHEMBL31179995	0.65	MAPT (1.00)	MAPTSTAT3MEN1KMT2A
Loganic Acid SCHEMBL29426077	0.65	MAPT (1.00)	MAPTSTAT3MEN1KMT2A
SCHEMBL31130793	0.64	PTPN1 (0.49)	MAPTSTAT3PTPN1MEN1KMT2A
Loganin SCHEMBL23805433	0.64	STAT3 (1.00)	MAPTSTAT3MEN1KMT2A
Loganin SCHEMBL21114425	0.64	STAT3 (1.00)	MAPTSTAT3MEN1KMT2A
Loganin SCHEMBL23805434	0.64	STAT3 (1.00)	MAPTSTAT3MEN1KMT2A
SCHEMBL22709360	0.64	SYNJ2 (0.51)	MAPTSTAT3PTPN1MEN1KMT2A
SCHEMBL19040200	0.64	SYNJ2 (0.51)	MAPTSTAT3PTPN1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
WO-2016169573-A1	SESQUITERPENE LACTONES AS POTENT AND BROAD SPECTRUM ANTIVIRAL COMPOUNDS AGAINST ALL GENOTYPES OF HEPATITIS C VIRUS (HCV)	ELSEBAI MAHMOUD FAHMI (EG)	2016-10-27	—	—	WO	disclosed