Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | STAT3 | P40763 | 10/20 | 0.37 |
| ▸ | SYNJ2 | O15056 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.34 |
| ▸ | SELE | P16581 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18180917 | 0.87 | MAPT (0.48) | PTPN1MAPTMEN1KMT2ASTAT3 | |
| SCHEMBL29425939 | 0.69 | MAPT (0.70) | MAPTMEN1KMT2ASTAT3 | |
| SCHEMBL30124791 | 0.67 | MEN1 (0.73) | MAPTMEN1KMT2ASTAT3 | |
| Trehalose SCHEMBL17819391 | 0.63 | MEN1 (0.56) | PTPN1MAPTMEN1KMT2AL3MBTL1 | |
| Goodyeroside SCHEMBL28930530 | 0.62 | PTPN1 (1.00) | PTPN1MAPTMEN1KMT2ASTAT3 | |
| Goodyeroside SCHEMBL29711425 | 0.62 | PTPN1 (1.00) | PTPN1MAPTMEN1KMT2ASTAT3 | |
| Goodyeroside SCHEMBL22043215 | 0.62 | PTPN1 (1.00) | PTPN1MAPTMEN1KMT2ASTAT3 | |
| SCHEMBL31130793 | 0.62 | PTPN1 (0.49) | PTPN1MAPTMEN1KMT2ASTAT3 | |
| Trehalose SCHEMBL23029503 | 0.62 | MEN1 (0.57) | PTPN1MAPTMEN1KMT2AL3MBTL1 | |
| SCHEMBL5357747 | 0.62 | MEN1 (0.57) | PTPN1MAPTMEN1KMT2AL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240293579-A1 | Composition Comprising Trim31 and Rhbdf2 for Treatment of NAFLD/NASH | CHONGQING MEIPULAN TECHNOLOGY CO., LTD (CN) | 2024-09-05 | — | — | US | claimed |
| US-20240293579-A1 | Composition Comprising Trim31 and Rhbdf2 for Treatment of NAFLD/NASH | CHONGQING MEIPULAN TECHNOLOGY CO., LTD (CN) | 2024-09-05 | — | — | US | disclosed |