Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 9/20 | 0.67 |
| ▸ | HSP90AB1 | P08238 | 9/20 | 0.67 |
| ▸ | MEN1 | O00255 | 3/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.55 |
| ▸ | RAB9A | P51151 | 3/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | MAPT | P10636 | 3/20 | 0.54 |
| ▸ | ATM | Q13315 | 2/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | MAOA | P21397 | 2/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.53 |
| ▸ | S100A4 | P26447 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8093017 | 0.93 | HSP90AA1 (0.67) | HSP90AA1HSP90AB1MEN1KMT2ARAB9A | |
| SCHEMBL5809304 | 0.88 | HSP90AA1 (0.76) | HSP90AA1HSP90AB1MEN1KMT2ARAB9A | |
| SCHEMBL8108753 | 0.81 | HSP90AA1 (0.67) | HSP90AA1HSP90AB1MEN1KMT2ARAB9A | |
| SCHEMBL17594608 | 0.81 | HSP90AA1 (0.67) | HSP90AA1HSP90AB1MEN1KMT2ARAB9A | |
| SCHEMBL31087717 | 0.80 | HSP90AA1 (1.00) | HSP90AA1HSP90AB1MEN1KMT2ARAB9A | |
| SCHEMBL6190569 | 0.80 | HSP90AA1 (1.00) | HSP90AA1HSP90AB1MEN1KMT2ARAB9A | |
| SCHEMBL7957265 | 0.80 | HSP90AA1 (0.65) | HSP90AA1HSP90AB1MEN1KMT2ARAB9A | |
| SCHEMBL11218447 | 0.79 | HSP90AA1 (0.63) | HSP90AA1HSP90AB1MEN1KMT2ARAB9A | |
| SCHEMBL8102411 | 0.79 | HSP90AA1 (0.63) | HSP90AA1HSP90AB1MEN1KMT2ARAB9A | |
| SCHEMBL18177881 | 0.79 | HSP90AA1 (0.63) | HSP90AA1HSP90AB1MEN1KMT2ARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160312253-A1 | Compounds for Increasing Lipid Synthesis and Storage | INVITROGEN CORPORATION | 2016-10-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160312253-A1 | Compounds for Increasing Lipid Synthesis and Storage | FASN, LIPC, SREBF2 | HSP90AA1 1907/4885HSP90AB1 1975/4885MEN1 2824/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.