SCHEMBL5809304

SCHEMBL5809304

CC(=O)NC1=C(NC(C)=O)C(=O)c2ccccc2C1=O

nearest known ligand 0.76

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSP90AA1 P07900 10/20 0.76
HSP90AB1 P08238 10/20 0.76
RAB9A P51151 3/20 0.66
MEN1 O00255 2/20 0.66
KMT2A Q03164 2/20 0.66
GAA P10253 1/20 0.66
ALDH1A1 P00352 3/20 0.64
MAPT P10636 3/20 0.64
ATM Q13315 2/20 0.64
L3MBTL1 Q9Y468 2/20 0.64
SMN1; SMN2 Q16637 2/20 0.64
MCL1 Q07820 2/20 0.64
KDM4E B2RXH2 1/20 0.64
MAPK1 P28482 1/20 0.64
HTT P42858 1/20 0.60
NPSR1 Q6W5P4 1/20 0.60
MAOA P21397 2/20 0.59
NPC1 O15118 1/20 0.59
S100A4 P26447 2/20 0.58
LMNA P02545 1/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8931021 0.89 RAB9A (0.73) HSP90AA1HSP90AB1RAB9AMEN1KMT2A
SCHEMBL11218447 0.89 HSP90AA1 (0.63) HSP90AA1HSP90AB1RAB9AMEN1KMT2A
SCHEMBL18182064 0.88 HSP90AA1 (0.67) HSP90AA1HSP90AB1RAB9AMEN1KMT2A
SCHEMBL17594608 0.88 HSP90AA1 (0.67) HSP90AA1HSP90AB1RAB9AMEN1KMT2A
SCHEMBL8093017 0.88 HSP90AA1 (0.67) HSP90AA1HSP90AB1RAB9AMEN1KMT2A
SCHEMBL8108753 0.88 HSP90AA1 (0.67) HSP90AA1HSP90AB1RAB9AMEN1KMT2A
SCHEMBL7955080 0.88 HSP90AA1 (0.61) HSP90AA1HSP90AB1RAB9AMEN1KMT2A
SCHEMBL7957265 0.87 HSP90AA1 (0.65) HSP90AA1HSP90AB1RAB9AMEN1KMT2A
SCHEMBL31087717 0.87 HSP90AA1 (1.00) HSP90AA1HSP90AB1RAB9AMEN1KMT2A
SCHEMBL6190569 0.87 HSP90AA1 (1.00) HSP90AA1HSP90AB1RAB9AMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2006107827-A1 SKIN BONDING PROCESS CREIGHTON UNIVERSITY (US) 2006-10-12 WO disclosed