Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDH1 | O75874 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | PIM1 | P11309 | 1/20 | 0.33 |
| ▸ | BACE1 | P56817 | 1/20 | 0.33 |
| ▸ | ELANE | P08246 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | NOX4 | Q9NPH5 | 1/20 | 0.30 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.30 |
| ▸ | CNR1 | P21554 | 1/20 | 0.30 |
| ▸ | CNR2 | P34972 | 1/20 | 0.30 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.30 |
| ▸ | RIPK1 | Q13546 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1818287 | 1.00 | IDH1 (0.34) | IDH1ALDH1A1MAPTHPGDNPSR1 | |
| SCHEMBL1820895 | 1.00 | IDH1 (0.34) | IDH1ALDH1A1MAPTHPGDNPSR1 | |
| SCHEMBL1821239 | 0.87 | NOX4 (0.34) | IDH1ALDH1A1MAPTHPGDNPSR1 | |
| SCHEMBL1818957 | 0.87 | GAA (0.35) | IDH1ALDH1A1MAPTHPGDNPSR1 | |
| SCHEMBL1818959 | 0.87 | GAA (0.35) | IDH1ALDH1A1MAPTHPGDNPSR1 | |
| SCHEMBL1824114 | 0.87 | BACE1 (0.37) | IDH1ALDH1A1MAPTHPGDNPSR1 | |
| SCHEMBL1824112 | 0.87 | BACE1 (0.37) | IDH1ALDH1A1MAPTHPGDNPSR1 | |
| SCHEMBL1821237 | 0.87 | NOX4 (0.34) | IDH1ALDH1A1MAPTHPGDNPSR1 | |
| SCHEMBL1942880 | 0.85 | ELANE (0.36) | ALDH1A1MAPTHPGDNPSR1LMNA | |
| SCHEMBL1821206 | 0.85 | ELANE (0.36) | ALDH1A1MAPTHPGDNPSR1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2315760-B1 | PIPERAZINE COMPOUNDS WITH HERBICIDAL EFFECT | BASF SE (DE) | 2013-03-06 | — | — | EP | disclosed |
| US-20110130286-A1 | Piperazine Compounds with Herbicidal Effect | BASF SE (DE) | 2011-06-02 | — | — | US | disclosed |
| EP-2315760-A1 | PIPERAZINE COMPOUNDS WITH HERBICIDAL EFFECT | BASF SE (DE) | 2011-05-04 | — | — | EP | disclosed |
| WO-2010012649-A1 | PIPERAZINE COMPOUNDS WITH HERBICIDAL EFFECT | BASF SE (DE) | 2010-02-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110130286-A1 | Piperazine Compounds with Herbicidal Effect | CAT, DDT, CIP2A | IDH1 179/4885ALDH1A1 71/4885MAPT 2873/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.