Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | PIM1 | P11309 | 2/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | BACE1 | P56817 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | NOX4 | Q9NPH5 | 4/20 | 0.33 |
| ▸ | NOX1 | Q9Y5S8 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | ITGB2 | P05107 | 1/20 | 0.31 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.31 |
| ▸ | ITGAL | P20701 | 1/20 | 0.31 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.31 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.31 |
| ▸ | DYRK2 | Q92630 | 1/20 | 0.30 |
| ▸ | CYBB | P04839 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1942880 | 1.00 | ELANE (0.36) | ELANEALDH1A1MAPTHPGDPIM1 | |
| SCHEMBL3021401 | 0.85 | MEN1 (0.38) | ELANEALDH1A1MAPTHPGDPIM1 | |
| SCHEMBL3021404 | 0.85 | MEN1 (0.38) | ELANEALDH1A1MAPTHPGDPIM1 | |
| SCHEMBL1818288 | 0.85 | IDH1 (0.34) | ELANEALDH1A1MAPTHPGDPIM1 | |
| SCHEMBL1818287 | 0.85 | IDH1 (0.34) | ELANEALDH1A1MAPTHPGDPIM1 | |
| SCHEMBL1820895 | 0.85 | IDH1 (0.34) | ELANEALDH1A1MAPTHPGDPIM1 | |
| SCHEMBL3025069 | 0.82 | XDH (0.51) | ALDH1A1MAPTNPSR1LMNAMEN1 | |
| SCHEMBL3024543 | 0.82 | HDAC1 (0.35) | ELANEALDH1A1MAPTHPGDPIM1 | |
| SCHEMBL3024546 | 0.82 | HDAC1 (0.35) | ELANEALDH1A1MAPTHPGDPIM1 | |
| SCHEMBL3025073 | 0.82 | XDH (0.51) | ALDH1A1MAPTNPSR1LMNAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2315760-B1 | PIPERAZINE COMPOUNDS WITH HERBICIDAL EFFECT | BASF SE (DE) | 2013-03-06 | — | — | EP | disclosed |
| US-20110130286-A1 | Piperazine Compounds with Herbicidal Effect | BASF SE (DE) | 2011-06-02 | — | — | US | disclosed |
| EP-2315760-A1 | PIPERAZINE COMPOUNDS WITH HERBICIDAL EFFECT | BASF SE (DE) | 2011-05-04 | — | — | EP | disclosed |
| WO-2010012649-A1 | PIPERAZINE COMPOUNDS WITH HERBICIDAL EFFECT | BASF SE (DE) | 2010-02-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110130286-A1 | Piperazine Compounds with Herbicidal Effect | CAT, DDT, CIP2A | ELANE 4540/4885ALDH1A1 71/4885MAPT 2873/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.