Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | RHOC | P08134 | 1/20 | 0.43 |
| ▸ | RHOA | P61586 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 4/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | KCNK3 | O14649 | 2/20 | 0.42 |
| ▸ | KCNK9 | Q9NPC2 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | CDK14 | O94921 | 3/20 | 0.41 |
| ▸ | CCNY | Q8ND76 | 3/20 | 0.41 |
| ▸ | JAK2 | O60674 | 1/20 | 0.40 |
| ▸ | TYK2 | P29597 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1819533 | 0.91 | KCNK3 (0.54) | MAPTMEN1KMT2ARAB9AKCNK3 | |
| SCHEMBL2260905 | 0.90 | KCNK3 (0.51) | MAPTRHOCRHOAMEN1KMT2A | |
| SCHEMBL2259443 | 0.89 | RAB9A (0.45) | MAPTMEN1KMT2ARAB9AHTT | |
| SCHEMBL1813161 | 0.89 | KCNK3 (0.52) | MAPTRHOCRHOAMEN1KMT2A | |
| SCHEMBL2258597 | 0.86 | KCNK3 (0.49) | MAPTMEN1KMT2ARAB9AHTT | |
| SCHEMBL1818358 | 0.84 | MEN1 (0.52) | MEN1KMT2ARAB9AKCNK3KCNK9 | |
| SCHEMBL1812611 | 0.84 | KMT2A (0.50) | MAPTMEN1KMT2ARAB9AHTT | |
| SCHEMBL2261615 | 0.81 | BRAF (0.44) | KCNK3KCNK9ALDH1A1 | |
| SCHEMBL1812039 | 0.77 | ALDH1A1 (0.51) | MAPTMEN1KMT2ARAB9AHTT | |
| SCHEMBL1812890 | 0.75 | MEN1 (0.48) | MAPTRHOCRHOAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2318358-A2 | ACYLAMINOBENZAMIDE DERIVATIVES | Bayer CropScience AG (DE) | 2011-05-11 | — | — | EP | disclosed |
| WO-2010015355-A2 | NOVEL ACYLAMINOBENZAMIDE DERIVATIVES | BAYER CROPSCIENCE AG (DE) | 2010-02-11 | — | — | WO | disclosed |