Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMO | O15229 | 2/20 | 0.38 |
| ▸ | F2RL3 | Q96RI0 | 4/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.37 |
| ▸ | GLA | P06280 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | GFER | P55789 | 1/20 | 0.37 |
| ▸ | CUL4A | Q13619 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.32 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11118115 | 0.76 | MAPT (0.36) | KDM4EGLAGAAALDH1A1HSD17B10 | |
| SCHEMBL1818472 | 0.76 | PIM1 (0.47) | KMOF2RL3KDM4EGLAALDH1A1 | |
| SCHEMBL3259550 | 0.74 | KDM4E (0.54) | KDM4EGAAALDH1A1HSD17B10CA12 | |
| SCHEMBL11117232 | 0.73 | GSTP1 (0.33) | KDM4EGLAGAAALDH1A1HPGD | |
| SCHEMBL6242111 | 0.72 | KDM4E (0.41) | KDM4EGLAALDH1A1HSD17B10HPGD | |
| SCHEMBL16708105 | 0.72 | KDM4E (0.51) | KMOF2RL3KDM4EGLAGAA | |
| SCHEMBL6545814 | 0.69 | FLT3 (0.54) | KDM4EGLAGAAALDH1A1HSD17B10 | |
| SCHEMBL10962225 | 0.69 | SLC16A3 (0.58) | KDM4EGLAGAAALDH1A1HSD17B10 | |
| SCHEMBL6240383 | 0.69 | KDM4E (0.58) | KDM4EGLAGAAALDH1A1HSD17B10 | |
| SCHEMBL4200612 | 0.68 | FLT3 (0.52) | KDM4EALDH1A1HPGDMAPTTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2493844-A2 | HALOGENALKYL-SUBSTITUTED AMIDES USED AS INSECTICIDES AND ACARICIDES | Bayer CropScience AG (DE) | 2012-09-05 | — | — | EP | disclosed |
| WO-2011054436-A2 | HALOGENALKYL-SUBSTITUTED AMIDES USED AS INSECTICIDES AND ACARICIDES | BAYER CROPSCIENCE AG (DE) | 2011-05-12 | — | — | WO | disclosed |