Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSTP1 | P09211 | 3/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | ABCC3 | O15438 | 1/20 | 0.33 |
| ▸ | PLIN1 | O60240 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | GSTA1 | P08263 | 1/20 | 0.33 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | MAP2K6 | P52564 | 1/20 | 0.33 |
| ▸ | HSPE1 | P61604 | 1/20 | 0.33 |
| ▸ | GSTO1 | P78417 | 1/20 | 0.33 |
| ▸ | PLIN5 | Q00G26 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11119025 | 0.86 | PAX8 (0.41) | GSTP1LMNAMAPTALDH1A1MEN1 | |
| SCHEMBL11118115 | 0.86 | MAPT (0.36) | GSTP1LMNAMAPTALDH1A1CYP3A4 | |
| Furacrinic Acid SCHEMBL11008170 | 0.81 | LMNA (0.42) | GSTP1LMNAMAPTALDH1A1MEN1 | |
| SCHEMBL1818474 | 0.73 | KMO (0.38) | LMNAMAPTALDH1A1MEN1TP53 | |
| SCHEMBL11010398 | 0.68 | LMNA (0.45) | GSTP1LMNAMAPTALDH1A1MEN1 | |
| SCHEMBL11010487 | 0.65 | LMNA (0.48) | GSTP1LMNAMAPTALDH1A1TP53 | |
| SCHEMBL6242111 | 0.65 | KDM4E (0.41) | MAPTALDH1A1MEN1TSHRHTT | |
| SCHEMBL11117277 | 0.63 | RECQL (0.32) | GSTP1LMNAMAPTALDH1A1MEN1 | |
| SCHEMBL6545814 | 0.62 | FLT3 (0.54) | LMNAALDH1A1MAOBMAOACA9 | |
| SCHEMBL6240383 | 0.61 | KDM4E (0.58) | MAPTALDH1A1MEN1TP53KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0122882-A1 | Steroids of the 20-spiroxan series, process for their preparation, pharmaceutical compositions containing them and use of these compositions | CIBA-GEIGY AG (CH) | 1984-10-24 | — | — | EP | disclosed |
| EP-0011818-B1 | MEDICAMENTS AND PHARMACEUTICAL COMPOSITIONS BASED ON ALDOSTERONE ANTAGONISTS AND DIURETICS AND PROCESS FOR THEIR MANUFACTURE | CIBA-GEIGY AG (CH) | 1983-01-19 | — | — | EP | disclosed |
| EP-0011818-A1 | Medicaments and pharmaceutical compositions based on aldosterone antagonists and diuretics and process for their manufacture | CIBA-GEIGY AG (CH) | 1980-06-11 | — | — | EP | disclosed |