Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA1A | P35348 | 13/20 | 0.46 |
| ▸ | L3MBTL3 | Q96JM7 | 4/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.43 |
| ▸ | GRM5 | P41594 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | MBTD1 | Q05BQ5 | 1/20 | 0.41 |
| ▸ | TP53BP1 | Q12888 | 1/20 | 0.41 |
| ▸ | L3MBTL4 | Q8NA19 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16823950 | 0.95 | ADRA1A (0.50) | ADRA1AL3MBTL3L3MBTL1GRM5MBTD1 | |
| Trifluoroacetic Acid SCHEMBL18185565 | 0.89 | ADRA1A (0.49) | ADRA1AL3MBTL3L3MBTL1KDM4EKMT2A | |
| Trifluoroacetic Acid SCHEMBL18185604 | 0.87 | GRM5 (0.51) | ADRA1AL3MBTL3L3MBTL1GRM5MBTD1 | |
| Trifluoroacetic Acid SCHEMBL18185583 | 0.86 | ADRA1A (0.46) | ADRA1AL3MBTL3L3MBTL1GRM5KMT2A | |
| Trifluoroacetic Acid SCHEMBL18185629 | 0.86 | ADRA1A (0.53) | ADRA1AL3MBTL3L3MBTL1MBTD1TP53BP1 | |
| Trifluoroacetic Acid SCHEMBL18185643 | 0.85 | ADRA1A (0.47) | ADRA1AL3MBTL3L3MBTL1GRM5MBTD1 | |
| Trifluoroacetic Acid SCHEMBL18185616 | 0.85 | ADRA1A (0.49) | ADRA1AL3MBTL3L3MBTL1MBTD1TP53BP1 | |
| Trifluoroacetic Acid SCHEMBL18185595 | 0.85 | CYP2D6 (0.45) | ADRA1AL3MBTL3L3MBTL1GRM5KDM4E | |
| SCHEMBL16845176 | 0.84 | ADRA1A (0.53) | ADRA1AL3MBTL3L3MBTL1KDM4EKMT2A | |
| SCHEMBL16823817 | 0.81 | GRM5 (0.56) | ADRA1AL3MBTL3L3MBTL1GRM5MBTD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160318866-A1 | SUBSTITUTED BIPIPERIDINYL DERIVATIVES | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2016-11-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160318866-A1 | SUBSTITUTED BIPIPERIDINYL DERIVATIVES | TNNI3, TNNC1, FABP3 | ADRA1A 1241/4885L3MBTL3 1001/4885L3MBTL1 1286/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.