SCHEMBL1818573

SCHEMBL1818573

CCC(=O)Nc1ccccc1C

nearest known ligand 0.70

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HPGD P15428 7/20 0.68
ALOX12 P18054 1/20 0.68
RAB9A P51151 3/20 0.64
NPC1 O15118 2/20 0.64
ALDH1A1 P00352 3/20 0.62
MAPT P10636 2/20 0.62
MAPK1 P28482 2/20 0.62
LMNA P02545 2/20 0.62
SMN1; SMN2 Q16637 1/20 0.62
HDAC3 O15379 1/20 0.62
HDAC4 P56524 1/20 0.62
HDAC1 Q13547 1/20 0.62
HDAC7 Q8WUI4 1/20 0.62
HDAC2 Q92769 1/20 0.62
HDAC10 Q969S8 1/20 0.62
HDAC11 Q96DB2 1/20 0.62
HDAC8 Q9BY41 1/20 0.62
HDAC6 Q9UBN7 1/20 0.62
HDAC9 Q9UKV0 1/20 0.62
HDAC5 Q9UQL6 1/20 0.62

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30738307 1.00 HPGD (0.68) HPGDALOX12RAB9ANPC1ALDH1A1
SCHEMBL2005846 0.88 RAB9A (0.73) HPGDALOX12RAB9ANPC1ALDH1A1
SCHEMBL29528561 0.88 RAB9A (0.73) HPGDALOX12RAB9ANPC1ALDH1A1
SCHEMBL8619629 0.87 MAPK1 (0.60) HPGDRAB9ANPC1ALDH1A1MAPT
SCHEMBL27846730 0.87 HPGD (0.54) HPGDALOX12RAB9ANPC1ALDH1A1
SCHEMBL7179910 0.87 RAB9A (0.63) HPGDALOX12RAB9ANPC1ALDH1A1
SCHEMBL10436820 0.85 HDAC3 (0.64) HPGDRAB9ANPC1ALDH1A1MAPT
SCHEMBL6658490 0.85 MAPK1 (0.69) HPGDALOX12RAB9ANPC1ALDH1A1
SCHEMBL5892350 0.84 HPGD (0.68) HPGDALOX12RAB9ANPC1ALDH1A1
SCHEMBL7828233 0.82 HPGD (0.66) HPGDALOX12RAB9ANPC1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 94 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2859069-B1 METHOD AND APPARATUS FOR TREATING PETROLEUM EQUIPMENT FERRARA MARCELLO (IT) 2020-10-14 EP claimed
CN-106233470-B The preparation method of the light absorbing layer of thin-film solar cells and the thin-film solar cells for utilizing it 韩国能源研究技术研究所 2019-07-12 CN claimed
CN-104193907-B A kind of high temperature resistant powder nitrile rubber 安徽皖东化工有限公司 2018-03-30 CN claimed
CN-107459535-A Polysubstituted quinoline coordinated iridium hybrid compound and preparation method and application thereof 南京工业大学 2017-12-12 CN claimed
CN-104193898-B A kind of salt-free high temperature resistant powder nitrile rubber 安徽皖东化工有限公司 2017-09-22 CN claimed
US-9328300-B2 Method, apparatus and chemical products for treating petroleum equipment FERRARA MARCELLO (IT) 2016-05-03 US claimed
EP-2859069-A1 METHOD AND APPARATUS FOR TREATING PETROLEUM EQUIPMENT Ferrara, Marcello (IT) 2015-04-15 EP claimed
WO-2013156228-A1 METHOD AND APPARATUS FOR TREATING PETROLEUM EQUIPMENT FERRARA MARCELLO (IT) 2013-10-24 WO claimed
US-20130270157-A1 METHOD, APPARATUS AND CHEMICAL PRODUCTS FOR TREATING PETROLEUM EQUIPMENT FERRARA MARCELLO (IT) 2013-10-17 US claimed
CN-102070484-B Method for preparing prilocainum or hydrochloride thereof BENGBU BBCA MEDICINE SCIENCE DEV CO LTD 2013-10-02 CN claimed
CN-102070484-A Method for preparing prilocainum or hydrochloride thereof BENGBU BBCA MEDICINE SCIENCE DEV CO LTD 2011-05-25 CN claimed
WO-1995020637-A2 HYDROCARBON OIL-AQUEOUS FUEL AND ADDITIVE COMPOSITIONS MEG S.N.C. DI SCOPELLITI SOFIA & C. (IT) 1995-08-03 WO claimed
US-20250154353-A1 RESIN COMPOSITION AND ARTICLE MADE THEREFROM ELITE ELECTRONIC MATERIAL (KUNSHAN) CO., LTD. (CN) 2025-05-15 US disclosed
US-20230140216-A1 COMBINATION THERAPY FOR TREATING MPS1 GAIN THERAPEUTICS SA (CH) 2023-05-04 US disclosed
US-20230127655-A1 MODULATORS OF ATP-BINDING CASSETTE TRANSPORTERS VERTEX PHARMACEUTICALS INCORPORATED (US) 2023-04-27 US disclosed
CN-111690135-B Diamine monomer containing adamantane structure, polyimide film, preparation method and application thereof 中国科学院宁波材料技术与工程研究所 2022-04-29 CN disclosed
US-5043442-A Process of preparing an isothiocyanate intermediate used in the preparation of xylazine CHEMSYN SCIENCE LABORATORIES (US) 1991-08-27 US disclosed
EP-0310732-A1 Process for the preparation of N-acyl-N-alkyl-2,6-dialkyl-3-chloroanilines CIBA-GEIGY AG (CH) 1989-04-12 EP disclosed
EP-0284555-A1 Process for the preparation of N-acyl-N-(oxazoliden-2-on-3-yl)-2,6-dialkyl-3-chloroanilines CIBA-GEIGY AG (CH) 1988-09-28 EP disclosed
US-4721797-A Process for the preparation of N-acyl-N-alkyl-2,6-dialkyl-3-chloroanilines CIBA-GEIGY CORPORATION (US) 1988-01-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230140216-A1 COMBINATION THERAPY FOR TREATING MPS1 IDUA, MAN2B1, GBA1 HPGD 3872/4885ALOX12 2544/4885RAB9A 2497/4885
US-20230127655-A1 MODULATORS OF ATP-BINDING CASSETTE TRANSPORTERS CFTR, ABCB1, ABCC2 HPGD 1644/4885ALOX12 2915/4885RAB9A 2071/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.