Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | TLR2 | O60603 | 1/20 | 0.42 |
| ▸ | MMP3 | P08254 | 2/20 | 0.41 |
| ▸ | MMP9 | P14780 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | BCHE | P06276 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | MMP1 | P03956 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1815850 | 1.00 | TSHR (0.50) | TSHRALDH1A1TDP1NPSR1TLR2 | |
| Sulfuric Acid SCHEMBL29684494 | 0.93 | TSHR (0.54) | TSHRALDH1A1TDP1NPSR1TLR2 | |
| Sulfuric Acid SCHEMBL1815849 | 0.93 | TSHR (0.54) | TSHRALDH1A1TDP1NPSR1TLR2 | |
| SCHEMBL1818338 | 0.93 | TSHR (0.54) | TSHRALDH1A1TDP1NPSR1TLR2 | |
| Sulfuric Acid SCHEMBL19900361 | 0.93 | TSHR (0.54) | TSHRALDH1A1TDP1NPSR1TLR2 | |
| Sulfuric Acid SCHEMBL19837752 | 0.93 | TSHR (0.54) | TSHRALDH1A1TDP1NPSR1TLR2 | |
| Sulfuric Acid SCHEMBL1818768 | 0.93 | TSHR (0.54) | TSHRALDH1A1TDP1NPSR1TLR2 | |
| SCHEMBL1819631 | 0.93 | TSHR (0.54) | TSHRALDH1A1TDP1NPSR1TLR2 | |
| Sulfuric Acid SCHEMBL31198220 | 0.93 | TSHR (0.54) | TSHRALDH1A1TDP1NPSR1TLR2 | |
| SCHEMBL27893120 | 0.92 | TSHR (0.53) | TSHRALDH1A1TDP1NPSR1TLR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3470402-A1 | CRYSTALLINE FORMS OF NEUROTROPHIN MIMETIC COMPOUNDS AND THEIR SALTS | Pharmatrophix Inc. (US) | 2019-04-17 | — | — | EP | claimed |
| US-9271986-B2 | Crystalline forms of neurotrophin mimetic compounds and their salts | PHARMATROPHIX, INC. (US) | 2016-03-01 | — | — | US | claimed |
| US-20150259278-A1 | CRYSTALLINE FORMS OF NEUROTROPHIN MIMETIC COMPOUNDS AND THEIR SALTS | PHARMATROPHIX, INC. | 2015-09-17 | — | — | US | claimed |
| EP-2900646-A1 | CRYSTALLINE FORMS OF NEUROTROPHIN MIMETIC COMPOUNDS AND THEIR SALTS | Pharmatrophix Inc. (US) | 2015-08-05 | — | — | EP | claimed |
| US-20130005731-A1 | CRYSTALLINE FORMS OF NEUROTROPHIN MIMETIC COMPOUNDS AND THEIR SALTS | PHARMATROPHIX, INC. (US) | 2013-01-03 | — | — | US | claimed |
| WO-2024192470-A1 | METHOD OF TREATING GLIOBLASTOMA OR OTHER CANCERS EXPRESSING P75 NEUROTROPHIN RECEPTOR | THE UNIVERSITY OF NEWCASTLE (AU) | 2024-09-26 | — | — | WO | disclosed |
| EP-3470402-B1 | CRYSTALLINE FORMS OF NEUROTROPHIN MIMETIC COMPOUNDS AND THEIR SALTS | PHARMATROPHIX INC (US) | 2021-01-06 | — | — | EP | disclosed |
| EP-3470402-A1 | CRYSTALLINE FORMS OF NEUROTROPHIN MIMETIC COMPOUNDS AND THEIR SALTS | Pharmatrophix Inc. (US) | 2019-04-17 | — | — | EP | disclosed |
| EP-2498782-B1 | CRYSTALLINE FORMS OF NEUROTROPHIN MIMETIC COMPOUNDS AND THEIR SALTS | PHARMATROPHIX INC (US) | 2019-01-09 | — | — | EP | disclosed |
| US-20180037559-A1 | CRYSTALLINE FORMS OF NEUROTROPHIN MIMETIC COMPOUNDS AND THEIR SALTS | PHARMATROPHIX, INC. | 2018-02-08 | — | — | US | disclosed |
| US-9884833-B2 | Crystalline forms of neurotrophin mimetic compounds and their salts | PHARMATROPHIX, INC. (US) | 2018-02-06 | — | — | US | disclosed |
| US-9884833-B2 | Crystalline forms of neurotrophin mimetic compounds and their salts | PHARMATROPHIX, INC. (US) | 2018-02-06 | — | — | US | disclosed |
| US-20150259278-A1 | CRYSTALLINE FORMS OF NEUROTROPHIN MIMETIC COMPOUNDS AND THEIR SALTS | PHARMATROPHIX, INC. | 2015-09-17 | — | — | US | disclosed |
| US-20150259278-A1 | CRYSTALLINE FORMS OF NEUROTROPHIN MIMETIC COMPOUNDS AND THEIR SALTS | PHARMATROPHIX, INC. | 2015-09-17 | — | — | US | disclosed |
| EP-2900646-A1 | CRYSTALLINE FORMS OF NEUROTROPHIN MIMETIC COMPOUNDS AND THEIR SALTS | Pharmatrophix Inc. (US) | 2015-08-05 | — | — | EP | disclosed |
| EP-2900646-A1 | CRYSTALLINE FORMS OF NEUROTROPHIN MIMETIC COMPOUNDS AND THEIR SALTS | Pharmatrophix Inc. (US) | 2015-08-05 | — | — | EP | disclosed |
| WO-2014052659-A1 | CRYSTALLINE FORMS OF NEUROTROPHIN MIMETIC COMPOUNDS AND THEIR SALTS | PHARMATROPHIX, INC. (US) | 2014-04-03 | — | — | WO | disclosed |
| US-20130005731-A1 | CRYSTALLINE FORMS OF NEUROTROPHIN MIMETIC COMPOUNDS AND THEIR SALTS | PHARMATROPHIX, INC. (US) | 2013-01-03 | — | — | US | disclosed |
| EP-2498782-A1 | CRYSTALLINE FORMS OF NEUROTROPHIN MIMETIC COMPOUNDS AND THEIR SALTS | Pharmatrophix Inc. (US) | 2012-09-19 | — | — | EP | disclosed |
| WO-2011060262-A1 | CRYSTALLINE FORMS OF NEUROTROPHIN MIMETIC COMPOUNDS AND THEIR SALTS | PHARMATROPHIX, INC. (US) | 2011-05-19 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150259278-A1 | CRYSTALLINE FORMS OF NEUROTROPHIN MIMETIC COMPOUNDS AND THEIR SALTS | BDNF, NTRK2, NGF | TSHR 1550/4885ALDH1A1 3092/4885TDP1 2315/4885 |
| US-20180037559-A1 | CRYSTALLINE FORMS OF NEUROTROPHIN MIMETIC COMPOUNDS AND THEIR SALTS | BDNF, NGF, NTRK2 | TSHR 885/4885ALDH1A1 4396/4885TDP1 1256/4885 |
| US-20130005731-A1 | CRYSTALLINE FORMS OF NEUROTROPHIN MIMETIC COMPOUNDS AND THEIR SALTS | BDNF, NGF, NTRK2 | TSHR 885/4885ALDH1A1 4396/4885TDP1 1256/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.